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CCL9 Protein

Ccl9 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE
Catalog No. ABIN7320489
  • Target See all CCL9 (Ccl9) Proteins
    CCL9 (Ccl9) (Chemokine (C-C Motif) Ligand 9 (Ccl9))
    Protein Type
    Recombinant
    Origin
    • 9
    • 2
    Mouse
    Source
    • 6
    • 4
    Escherichia coli (E. coli)
    Purpose
    Recombinant Mouse CCL9/MIP-1-γ Protein
    Sequence
    Gln22-Gln122
    Characteristics
    Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.
    Purity
    > 90 % as determined by SDS-PAGE
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl,300 mM NaCl, pH 8.0.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CCL9 (Ccl9) (Chemokine (C-C Motif) Ligand 9 (Ccl9))
    Alternative Name
    CCL9/MIP-1-gamma (Ccl9 Products)
    Synonyms
    CCF18 Protein, MRP-2 Protein, Scya10 Protein, Scya9 Protein, chemokine (C-C motif) ligand 9 Protein, Ccl9 Protein
    Background

    Background: C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.

    Synonym: C-C motif chemokine 9, CCF18, Macrophage inflammatory protein 1-gamma, Macrophage inflammatory protein-related protein 2, Small-inducible cytokine A9, Scya10,Scya9 and CCL9.

    Molecular Weight
    11.6 kDa
    UniProt
    P51670
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