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The product of CKLF is a cytokine. Additionally we are shipping CKLF Kits (27) and and many more products for this protein.
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Data indicate that leukocyte-infiltrate derived chemokine-like factor (CKLF) expression is a candidate biomarker of favorable prognosis.
CKLF1 expression was up-regulated in synovim from rheumatoid arthritis and ankylosing spondylitis patients.
Chemokine-like factor 1 is over-expressed in patients with atopic dermatitis.
CKLF1 can induce proliferation and inhibit apoptosis of human vascular smooth muscle cell through the down-regulation of Bax (show BAX Antibodies) and Caspase-3 (show CASP3 Antibodies) and the up-regulation of Bcl-2 (show BCL2 Antibodies) expression.
The expression of CKLF1 is up-regulated in atherosclerotic plaques.
CKLF1-C19 and -C27 can stimulate antigen-presenting capability of dendritic cells
CKLF1 could increase the proliferation of human bone marrow hematopoietic progenitor cells and colony formation
Results confirm that the secreted peptides of CKLF1, C27 and C19, have functional activation via CCR4 (show CCR4 Antibodies).
Chemokine-like factor expression is differentially regulated in myoblasts and myotubes and thrombin (show F2 Antibodies) could be a strong regulator for its expression
NF-kappaB (show NFKB1 Antibodies) signaling pathway was involved in the asthmatic change induced by CKLF1, among which CCR4 (show CCR4 Antibodies) might play a crucial role
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).
chemokine-like factor 1
, chemokine-like factor 2
, chemokine-like factor 3
, chemokine-like factor 4
, transmembrane proteolipid
, chemokine-like factor 6