anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antibodies

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Additionally we are shipping Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (77) and Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteins (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHI3L1 12654 Q61362
CHI3L1 1116 P36222
CHI3L1 89824 Q9WTV1
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Top anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies at antibodies-online.com

Showing 10 out of 114 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, WB WB Suggested Anti-CHI3L1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of YKL-40 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot analysis of CHI3L1 using anti-CHI3L1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: mouse RAW264.7 whole cell lysates, Lane 2: mouse HEPA1-6 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CHI3L1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CHI3L1 at approximately 43KD. The expected band size for CHI3L1 is at 43KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human Serum. 100 μg Log in to see 13 to 16 Days
$332.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$727.83
Details
Human Mouse Un-conjugated ELISA, WB Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - SW480 cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CHI3L1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Western Blot: Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - Cell lysates of HepG2 (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CHI3L1 (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 12 to 15 Days
$485.88
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of extracts of THP1, using CHI3L1antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276840 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extract of various cells, using CHI3L1 antibody. 100 μL Log in to see 16 Days
$334.77
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) HepG2 cells probed with Rabbit Anti-CHI3L1 Polyclonal Antibody  Alexa Fluor 488 Secondary 100 μL Log in to see 14 to 21 Days
$306.90
Details

Top referenced anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antibodies

  1. Human Monoclonal CHI3L1 Primary Antibody for ELISA - ABIN2472953 : Iwarson: [The pattern of non-A, non-B hepatitis is more and more evident. A new test for diagnosis of hepatitis C makes it possible to mass screen blood donors]. in Läkartidningen 1990 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal CHI3L1 Primary Antibody for IF, WB - ABIN2784693 : Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Interaction Partners

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. CHI3L1 may be a previously unrecognized biomarker for diagnosing Gaucher Diseases (GD) and for evaluating the therapeutic effects of new GD drug.

  2. CHI3L1 deficiency in donor splenocytes dramatically increased the severity of aGVHD through enhancing Tfh cell differentiation

  3. miR (show MLXIP Antibodies)-24 serves as a molecular regulator in S. aureus-induced macrophage polarization through targeting of CHI3L1 and regulation of the MAPK (show MAPK1 Antibodies) pathway

  4. The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo

  5. CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (show S100A9 Antibodies) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (show S100A9 Antibodies) receptor, RAGE (show AGER Antibodies) (Receptor for Advanced Glycation End products).

  6. IL-18 (show IL18 Antibodies) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (show IL18 Antibodies)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  7. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  8. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  9. Results do not support a role of BRP (show GDF5 Antibodies)-39 in the pathogenesis of experimental autoimmune encephalitis.

  10. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. Plasma YKL-40 distinguishes between patients with features of asthma-chronic obstructive pulmonary disorder (COPD (show ARCN1 Antibodies)) overlap (ACO (show KLK15 Antibodies)) and COPD (show ARCN1 Antibodies) patients.

  2. CHI3L1 expression is a novel biomarker for the prognosis of gastric cancer and these findings have thus identified CHI3L1/CD44 (show CD44 Antibodies) axis as a vital pathway and potential therapeutic target in gastric cancer

  3. Gene expressions of YKL-40 and CD36 (show CD36 Antibodies) were significantly higher in patients with T2DM (>5 yr) with hypertension compared to healthy controls (P=0.006). In addition, a significant increase in serum levels of sCD36, PPAR-gamma (show PPARG Antibodies) and YKL-40 was observed in patients with T2DM (>5 yr) with hypertension compared to healthy controls

  4. YKL-40 was highly elevated in patients with ESRD on HD, and dialysis reduced serum YKL-40 concentrations approximately one-sixth. YKL-40 measured after dialysis was independently associated with mortality in HD patients.

  5. Review/Meta-analysis: YKL-40 may be implicated in bronchial inflammation and remodeling in COPD (show ARCN1 Antibodies) and may be considered as a useful biomarker for COPD (show ARCN1 Antibodies) diagnosis and monitoring.

  6. YKL-40 is a glycoprotein - a potential marker for active inflammatory process - with proven predictive value in a number of diseases that evolve with inflammation, remodeling of the extracellular matrix, or development of fibrosis.

  7. TMEM219 plays a critical role in Chi3l1-induced IL-13Ralpha2 mediated signalling and tissue responses.

  8. Our present data reveal the crucial role of CHI3L1 in the formation of vasculogenic mimicry, which may contribute to tumour aggressiveness of cervical cancer

  9. there was a negative correlation between YKL-40 and TLR4 (show TLR4 Antibodies) expression in chronic sinusitis patients with nasal polyps. YKL-40 and TLR4 (show TLR4 Antibodies) interacted with each other to activate NF-kappaB (show NFKB1 Antibodies) and promote disease progression.

  10. CHI3L1 may be a previously unrecognized biomarker for diagnosing Gaucher Diseases (GD) and for evaluating the therapeutic effects of new GD drug.

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) interaction partners

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antigen Profile

Protein Summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Gene names and symbols associated with CHI3L1

  • chitinase-like 1 (Chil1) antibody
  • chitinase 3 like 1 (CHI3L1) antibody
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1) antibody
  • chitinase 3 like 1 (Chi3l1) antibody
  • ASRT7 antibody
  • AW208766 antibody
  • BP40 antibody
  • Brp39 antibody
  • CGP-39 antibody
  • Chil1 antibody
  • CLP-1 antibody
  • GP-39 antibody
  • GP38K antibody
  • GP39 antibody
  • HC-gp39 antibody
  • HCGP-3P antibody
  • hCGP-39 antibody
  • MGP-40 antibody
  • SPC-40 antibody
  • SPS-40 antibody
  • YKL-40 antibody
  • YKL40 antibody
  • YYL-40 antibody

Protein level used designations for CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPECIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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