Chordin-Like 1 Proteins (CHRDL1)

CHRDL1 encodes an antagonist of bone morphogenetic protein 4. Additionally we are shipping Chordin-Like 1 Antibodies (54) and Chordin-Like 1 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRDL1 91851 Q9BU40
CHRDL1 83453 Q920C1
Rat CHRDL1 CHRDL1 363455 Q76LD0
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Top Chordin-Like 1 Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Chicken His tag   1 mg Log in to see 60 to 71 Days
Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse T7 tag,His tag 100 μg Log in to see 15 to 18 Days

CHRDL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,

More Proteins for Chordin-Like 1 (CHRDL1) Interaction Partners

Human Chordin-Like 1 (CHRDL1) interaction partners

  1. Finally, in vivo experiments confirmed that CHRDL1 acted as a tumor suppressor gene in suppressing tumor growth and metastasis

  2. Results show that Chrdl1 expression is upregulated in numerous breast cancer cells following TGF-beta stimulation and demonstrated that Chrdl1 acts as an inhibitor of BMP4-induced migration and invasion.

  3. These studies have identified and validated new factors enriched in juvenile chondrocytes as compared to adult chondrocytes including secreted extracellular matrix factors chordin-like 1 (CHRDL1) and microfibrillar-associated protein 4 (MFAP4).

  4. We provide the initial confirmation that X-linked megalocornea is associated with mutations in the CHRDL1 gene.

  5. CHRDL1 plays a key role in cornea homeostasis as evidenced by disease causing mutations in X-linked megalocornea.

  6. The detection of mutations in the CHRDL1 gene is useful for differential diagnosis with different forms of megalocornea.

  7. Novel CHRDL1 mutations in ten families with X-linked megalocornea, are reported.

  8. CHRDL1 is expressed in the developing human cornea and anterior segment in addition to the retina.

  9. Hypoxia-induced upregulation of CHL-1 alters the homeostatic balance between BMP-4 and VEGF to synergize with VEGF in driving retinal angiogenesis.

  10. reports the cloning of chick ventroptin and its importance in topographic retinotectal projection

Mouse (Murine) Chordin-Like 1 (CHRDL1) interaction partners

  1. CHRDL-1 is a new regulatory target of miR-134 during cortical neuronal differentiation; this is a novel role for miR-134 in the modulation of cortical development.

  2. Reperfusion injury of proximal kidney tubules causes a reduction of Chrdl1 expression.

Chordin-Like 1 (CHRDL1) Protein Profile

Protein Summary

This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with Chordin-Like 1 Proteins (CHRDL1)

  • chordin like 1 (CHRDL1)
  • chordin-like 1 (Chrdl1)
  • chordin-like 1 (CHRDL1)
  • chordin-like 1 (chrdl1)
  • chl protein
  • CHL1 protein
  • da141h5.1 protein
  • Kjr protein
  • Neurogenesin-1 protein
  • Ng1 protein
  • nrln1 protein
  • vopt protein

Protein level used designations for Chordin-Like 1 Proteins (CHRDL1)

chordin-like protein 1 , neuralin 1 , neuralin-1 , neurogenesin-1 , ventroptin , ventroptin-alpha , ventroptin-beta , likely ortholog of mouse neuralin 1 , chordin-like 1 , chordin-like protein 1-like , kohjirin , neurogenesin 1

91851 Homo sapiens
83453 Mus musculus
373985 Gallus gallus
492066 Canis lupus familiaris
540275 Bos taurus
100144642 Xenopus (Silurana) tropicalis
100435136 Pongo abelii
100481754 Ailuropoda melanoleuca
100521058 Sus scrofa
100591854 Nomascus leucogenys
363455 Rattus norvegicus
100059105 Equus caballus
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