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CHD5 encodes a member of the chromodomain helicase DNA-binding protein family. Additionally we are shipping CHD5 Kits (11) and and many more products for this protein.
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Data show that chromodomain helicase DNA binding protein 5 (CHD5) acted as a functional tumor suppressor and was frequently silenced by promoter CpG methylation in renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)).
CHD5 (show WRB Antibodies) may act as a tumor suppressor gene in NSCLC.
Authors identified the CHD5 (show WRB Antibodies) as a direct target of miR (show MLXIP Antibodies)-454. CHD5 (show WRB Antibodies) was downregulated in HCC (show FAM126A Antibodies) tissues and cell lines and the expression level of CHD5 (show WRB Antibodies) was inversely correlated with the expression of miR (show MLXIP Antibodies)-454 in HCC (show FAM126A Antibodies) tissues.
Data show a mutual suppression regulation between chromodomain helicase DNA binding protein 5 (CHD5) and enhancer of zeste homolog 2 (EZH2 (show EZH2 Antibodies), which may provide new insights into their potential therapeutic significance for hepatocellular carcinoma (HCC (show FAM126A Antibodies)).
CHD5 (show WRB Antibodies) methylation of rectal cancer has a great effect in influencing its clinical and pathological features.
Study shows that CHD5 (show WRB Antibodies) is a Nucleosome remodeling and deacetylase complex-associated transcriptional repressor and identifies WEE1 (show WEE1 Antibodies) as one of the CHD5 (show WRB Antibodies)-regulated genes that may link CHD5 (show WRB Antibodies) to tumor suppression.
Low CHD5 (show WRB Antibodies) expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.
CHD5 (show WRB Antibodies) is a potential tumour suppressor gene epigenetically silenced in hepatocellular carcinoma.
The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping.
repression of CHD5 (show WRB Antibodies) gene expression in human leukemia is mediated in part by DNA methylation (show HELLS Antibodies) of its promoter.
Chd5 represses murine endogenous retrovirus-L (MuERV-L/MERVL), an endogenous retrovirus-derived retrotransposon, by regulating H3K27me3 and H3.1/H3.2 function.
Chd5 (show WRB Antibodies) is a multi-faceted mediator of histone-to-protamine replacement and is important in the cascade of molecular events underlying this process of extensive chromatin remodelling.
Our data indicate that CHD5 (show WRB Antibodies) is required for normal spermiogenesis, especially for spermatid chromatin condensation.
Chd5 (show WRB Antibodies) expression is retained at high levels in differentiated neurons of the adult mouse.
These findings provide insights into the regulatory role of CHD5 (show WRB Antibodies) during neurogenesis and suggest how inactivation of this candidate tumor suppressor might contribute to neuroblastoma (show ARHGEF16 Antibodies).
Chd5 (show WRB Antibodies) binds the unmodified N terminus of H3 through its tandem plant homeodomains (PHDs).
CHD5 (show WRB Antibodies) regulates expression of neuronal genes, cell cycle genes and remodeling genes, and is linked to regulation of genes implicated in aging and Alzheimer's disease.
the association of between miR (show MLXIP Antibodies)-211-regulated CHD5 (show WRB Antibodies) expression and CHD5 (show WRB Antibodies) function in colorectal tumorigenesis
This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma.
ATP-dependent helicase CHD5
, chromodomain-helicase-DNA-binding protein 5
, chromodomain helicase DNA binding protein 5
, Coronary heart disease, susceptibility to, 5
, chromodomain-helicase-DNA-binding protein 5-like