anti-Chromosome 10 Open Reading Frame 2 Antibodies

C10ORF2 encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication.

Data Quality
  • 1
  • 18
  • 1
Type
  • 74
    Primary
Antigen
  • 74
Reactivity
  • 73
  • 34
  • 32
  • 3
  • 3
Application
  • 49
  • 25
  • 24
  • 13
  • 6
Host
  • 72
  • 2
Clonality
  • 72
  • 2
Clone
  • 2
Binding Specificity
  • 13
  • 9
  • 8
  • 4
  • 4
Conjugate
  • 31
  • 6
  • 4
  • 4
  • 3
  • 3
Isotype
  • 43
  • 2
  • 2
Format
  • 51
  • 7
Suggested next Filters
74 Products
ReactivityCow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2775251
$319.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN633374
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN633375
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN5014483
$245.00
100 μL
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IHC, WB
Order details Cat. No. ABIN6260353
$390.77
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application IF/ICC, WB
Order details Cat. No. ABIN2975393
$422.09
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application EIA, IHC (p), WB
Order details Cat. No. ABIN954086
$522.50
0.4 mL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN5533042
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN2996954
$590.93
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6137714
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application IF, WB
Order details Cat. No. ABIN6137715
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityCow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
Application WB
Order details Cat. No. ABIN2775250
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityMouse (Murine)
Application WB
Order details Cat. No. ABIN6290656
$309.73
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF (p), IHC (p), WB
Order details Cat. No. ABIN1385971
$327.80
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application IF, IHC, WB
Order details Cat. No. ABIN1876491
$368.95
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
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Chromosome 10 Open Reading Frame 2 (C10ORF2) Antigen Profile

Protein Summary

This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with C10ORF2

  • twinkle mtDNA helicase L homeolog (twnk.L) antibody
  • twinkle mtDNA helicase (TWNK) antibody
  • twinkle mtDNA helicase (Twnk) antibody
  • ATXN8 antibody
  • C6H10orf2 antibody
  • D19Ertd626e antibody
  • IOSCA antibody
  • MTDPS7 antibody
  • PEO antibody
  • PEO1 antibody
  • PEOA3 antibody
  • SANDO antibody
  • SCA8 antibody
  • Twinl antibody

Protein level used designations for C10ORF2

uncharacterized protein LOC414487 , twinkle protein, mitochondrial , T7 gp4-like protein with intramitochondrial nucleoid localization , T7 helicase-related protein with intramitochondrial nucleoid localization , T7-like mitochondrial DNA helicase , ataxin 8 , mitochondrial twinkle protein , progressive external ophthalmoplegia 1 protein , progressive external ophthalmoplegia 1 , progressive external ophthalmoplegia 1 homolog , progressive external ophthalmoplegia 1 protein homolog

GENE ID SPECIES
414487 Xenopus laevis
710958 Macaca mulatta
56652 Homo sapiens
486845 Canis lupus familiaris
309441 Rattus norvegicus
425626 Gallus gallus
226153 Mus musculus