anti-Chromosome 5 Open Reading Frame 13 (C5orf13) Antibodies

Human Chromosome 5 Open Reading Frame 13 (C5orf13) interaction partners

1. P311 is a novel TGFbeta1/Smad signaling-mediated regulator of transdifferentiation in epidermal stem cells during cutaneous wound healing.

2. P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation.

3. These studies demonstrate that P311 is required for the production of normal cutaneous scars

4. P311 plays a key role in renal fibrosis via TGFbeta1/Smad signaling, which could be a novel target for the management of renal fibrosis.

5. Novel RNA-binding protein P311 binds eIF3b to promote translation of TGF-beta1, TGF-beta2, TGF-beta3.

6. P311 may promote the migration of ESCs both in micewith superficial partial-thickness burns and in an injured cell model in vitro, and it may play an important role in wound healing.

7. Protein HYI may closely bind with protein P311 by an alpha helix in hypertrophic scar fibroblasts.

8. P311 and ITGB4BP expression was elevated in non-small cell lung cancer, possibly indicative of a new signaling pathway.

9. P311 may be involved in the pathogenesis of hypertrophic scar via induction of a myofibrobla

10. role for P311 in inducing TGF-beta1-independent myofibroblast transformation

11. These results suggest a role for levels of P311 in regulating glioma motility and invasion through the reorganization of actin cytoskeleton at the cell periphery.

12. P311 expression is tightly regulated during the critical periods of alveolar formation, and that under pathologic conditions, its relative absence may contribute to failure of alveolar regeneration and lead to the development of human emphysema.

Mouse (Murine) Chromosome 5 Open Reading Frame 13 (C5orf13) interaction partners

1. P311 is a novel TGFbeta1/Smad signaling-mediated regulator of transdifferentiation in epidermal stem cells during cutaneous wound healing.

2. P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation.

3. These studies demonstrate that P311 is required for the production of normal cutaneous scars

4. P311 plays a key role in renal fibrosis via TGFbeta1/Smad signaling, which could be a novel target for the management of renal fibrosis.

5. P311 is central to reactive oxygen species-mediated hepatic stellate cell migration induced by different chemokines.

6. P311 is the first protein identified to modulate TGF-beta translation and the first pan-regulator of TGF-beta expression.

7. P311 may promote the migration of ESCs both in micewith superficial partial-thickness burns and in an injured cell model in vitro, and it may play an important role in wound healing.

8. role for P311 in inducing TGF-beta1-independent myofibroblast transformation

9. P311 expression is tightly regulated during the critical periods of alveolar formation, and that under pathologic conditions, its relative absence may contribute to failure of alveolar regeneration and lead to the development of human emphysema.

10. formalin-induced avoidance behavior, which reflects pain-related negative emotion, was significantly attenuated in P311-/- mice

11. these data establish P311 as playing an important role in learning and memory processes and emotional responses

12. A novel role for P311 in an alternative pathway of lipid-droplet accumulation that is induced by the regeneration-inducing molecule retinoic acid.