Chromosome 5 Open Reading Frame 39 Proteins (C5orf39)

May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.. Additionally we are shipping Chromosome 5 Open Reading Frame 39 Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C5orf39 389289 Q3ZCQ2
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Top Chromosome 5 Open Reading Frame 39 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details

C5orf39 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Chromosome 5 Open Reading Frame 39 (C5orf39) Interaction Partners

Human Chromosome 5 Open Reading Frame 39 (C5orf39) interaction partners

  1. Overexpression of AX2R significantly inhibited cell proliferation, migration and tube formation in both types of endothelial cells and increased the expression of KLF2 (show KLF2 Proteins), mediating VEGF (show VEGFA Proteins) and VEGFR2 (show KDR Proteins).

  2. Data highlighted the crucial role of AXIIR in reducing Mum2C cell viability through inducing apoptosis, while autophagy played a protective role in this process.

  3. these subsequent effects might be via suppressing the expression of matrix metalloproteinase 2 (show MMP2 Proteins) and matrix metalloproteinase 9 (show MMP9 Proteins). ... AXIIR participates in angiogenesis, and may be a potential therapeutic target for angiogenesis related diseases

  4. AXIIR acts as a novel inducer of apoptosis in human cells, partially through activating Caspase-8 (show CASP8 Proteins).

  5. Results show that AXII and AXIIR play important roles in multiple myeloma (MM) and that targeting the AXII/AXIIR axis may be a novel therapeutic approach for MM.

  6. analysis of the annexin II receptor on human marrow stromal cells

  7. annexin II and its receptor axis play a central role in prostate cancer metastasis, and prostate cancer utilizes the hematopoietic stem cell homing mechanisms to gain access to the niche.

Chromosome 5 Open Reading Frame 39 (C5orf39) Protein Profile

Protein Summary

May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.

Gene names and symbols associated with C5orf39

  • annexin A2 receptor (ANXA2R)
  • AX2R protein
  • AXIIR protein
  • C5orf39 protein

Protein level used designations for C5orf39

annexin II receptor , annexin-2 receptor

GENE ID SPECIES
389289 Homo sapiens
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