anti-Chromosome 6 Open Reading Frame 25 (C6orf25) Antibodies

C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. Additionally we are shipping C6orf25 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C6orf25 406865 Q6MG59
C6orf25 80739 O95866
C6orf25 106722  
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Top anti-C6orf25 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-C6orf25 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μg 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using C6orf25 antibody. Western blot analysis of extracts of various cell lines, using C6orf25 antibody (ABIN4903093) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB 100 μg 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse Testis lysates probed with Anti-C6orf25 Polyclonal Antibody, Unconjugated (ABIN2171807) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 90min in 37˚C 100 μL 14 to 21 Days
$317.90
Details
Human Mouse Un-conjugated WB Western Blot analysis of C6orf25 expression in transfected 293T cell line by C6orf25 MaxPab polyclonal antibody.Lane1:C6orf25 transfected lysate(26.07 KDa).Lane2:Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB C6ORF25 antibody used at 1 ug/ml to detect target protein. 50 μg 9 to 11 Days
$449.29
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL 3 to 7 Days
$416.90
Details

More Antibodies against C6orf25 Interaction Partners

Human Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. Case report of a novel MPIG6B gene mutation in a Chinese boy with pancytopenia and splenomegaly.

  2. Autosomal recessive loss-of-function mutations in G6b-B (MPIG6B) cause congenital macrothrombocytopenia with focal myelofibrosis. G6b-B has orthologous physiological functions in human and mice regulating megakaryocyte and platelet production and function.

  3. G6B seems to act through an autosomal recessive mode of disease transmission in this family and regarded as the gene responsible for the observed hematological disorder.

  4. Heparin might modulate the interaction of G6b with its as yet unidentified protein ligand

  5. G6B represents a novel inhibitory receptor found on the surface of platelets

  6. G6b-B expression is highly restricted to peripheral CD4+ T cells and up-regulated by the IL-4-induced STAT6 pathway, suggesting that G6b-B is involved in regulation of the immune response by CD4+ T cell-mediated and IL-4 induced regulatory mechanisms.

  7. G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2.

Mouse (Murine) Chromosome 6 Open Reading Frame 25 (C6orf25) interaction partners

  1. Uncoupling of G6b-B from Shp1 and Shp2 results in severe macrothrombocytopenia and aberrant platelet function.

  2. these findings establish G6b-B as a major inhibitory receptor regulating megakaryocyte activation, function, and platelet production.

C6orf25 Antigen Profile

Protein Summary

This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with C6orf25

  • megakaryocyte and platelet inhibitory receptor G6b (Mpig6b) antibody
  • megakaryocyte and platelet inhibitory receptor G6b (MPIG6B) antibody
  • C6orf25 antibody
  • G6B antibody
  • LOC745085 antibody
  • NG31 antibody

Protein level used designations for C6orf25

protein G6b , immunoglobulin receptor , G6B protein , G6b protein , ITIM-receptor G6b-B

GENE ID SPECIES
406865 Rattus norvegicus
80739 Homo sapiens
745085 Pan troglodytes
106722 Mus musculus
617577 Bos taurus
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