anti-Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) Antibodies

CPSF3 encodes a member of the metallo-beta-lactamase family. Additionally we are shipping CPSF3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CPSF3 51692 Q9UKF6
CPSF3 298916  
CPSF3 54451 Q9QXK7
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Top anti-CPSF3 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CPSF3 Antibody Titration:  5.0ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate 100 μL 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CPSF3 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate Rabbit Anti-CPSF3 Antibody  Paraffin Embedded Tissue: Human Liver Cellular Data: Liver cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated EIA, WB Western blot of CPSF3 Antibody  analysis in A375 cell line lysates (35ug/lane).This demonstrates the CPSF3 antibody detected the CPSF3 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Mouse Un-conjugated ELISA, WB CPSF3 monoclonal antibody (M06), clone 1H8. Western Blot analysis of CPSF3 expression in Hela S3 NE . CPSF3 monoclonal antibody (M06), clone 1H8. Western Blot analysis of CPSF3 expression in NIH/3T3. 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to CPSF3 on HeLa cell. [antibody concentration 10 ug/ml] CPSF3 monoclonal antibody (M01), clone 6E6 Western Blot analysis of CPSF3 expression in Hela S3 NE . 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB CPSF3 polyclonal antibody (A01), Lot # 060613JCS1 Western Blot analysis of CPSF3 expression in Hela S3 NE . CPSF3 polyclonal antibody (A01), Lot # 060613JCS1. Western Blot analysis of CPSF3 expression in NIH/3T3. 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Un-conjugated WB Western blot analysis in A375 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details

Top referenced anti-CPSF3 Antibodies

  1. Human Polyclonal CPSF3 Primary Antibody for WB - ABIN526863 : Johansson, Somberg, Li, Backström Winquist, Fay, Ryan, Pim, Banks, Schwartz: HPV-16 E2 contributes to induction of HPV-16 late gene expression by inhibiting early polyadenylation. in The EMBO journal 2012 (PubMed)

More Antibodies against CPSF3 Interaction Partners

Human Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3) interaction partners

  1. the molecular mechanism that recruits the CPSF73 endonuclease to histone pre-mRNAs

  2. The data support a model where Star-PAP binds to the pre-mRNA, recruits the CPSF complex to the 3'-end of pre-mRNA and then defines cleavage by CPSF 73 and subsequent polyadenylation of its target mRNAs.

  3. up-regulated by HIV-1 TAT protein; this could represent a novel mechanism by which HIV increases mRNA processing, causing an increase in both cell and viral gene expression.

  4. crystal structures of human CPSF-73 at 2.1 A resolution, complexed with zinc ions and a sulphate that might mimic the phosphate group of the substrate; CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

  5. this study identifies CPSF-73 as an important regulatory protein that represses the basal transcriptional activity of the HIV-1 LTR promoter

  6. Conserved residues in CPSF-73 and CPSF2 are required for assembly of the endonuclease activity that cleaves histone pre-mRNAs.

  7. CSR1 appears to induce cell death through a novel mechanism by hijacking a critical RNA processing enzyme CPSF3.

  8. Degradation of the downstream cleavage product (DCP) does not depend on the Xrn2 5' exonuclease, suggesting that CPSF-73 degrades the DCP both in vitro and in vivo.

  9. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.

CPSF3 Antigen Profile

Protein Summary

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.

Gene names and symbols associated with CPSF3

  • cleavage and polyadenylation specific factor 3 (CPSF3) antibody
  • cleavage and polyadenylation specific factor 3 (cpsf3) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (CpipJ_CPIJ011955) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (CMU_024380) antibody
  • cleavage and polyadenylation specificity factor subunit 3 (PITG_07110) antibody
  • cleavage and polyadenylation specific factor 3 L homeolog (cpsf3.L) antibody
  • cleavage and polyadenylation specific factor 3, 73kDa (CPSF3) antibody
  • cleavage and polyadenylation specific factor 3 (Cpsf3) antibody
  • cleavage and polyadenylation specificity factor 3 (Cpsf3) antibody
  • CPSF-73 antibody
  • CPSF3 antibody
  • CPSF73 antibody
  • si:dkey-81b15.1 antibody
  • wu:fc32f10 antibody
  • zgc:101655 antibody

Protein level used designations for CPSF3

cleavage and polyadenylation specificity factor 73 kDa subunit , cleavage and polyadenylation specificity factor subunit 3 , cleavage and polyadenylation specificity factor 3 , cleavage and polyadenylation specific factor 3, 73kDa , cleavage and polyadenylation specificity factor subunit 3-like , mRNA 3'-end-processing endonuclease CPSF-73 , CPSF 73 kDa subunit

GENE ID SPECIES
459017 Pan troglodytes
448456 Xenopus (Silurana) tropicalis
694036 Macaca mulatta
421929 Gallus gallus
100174072 Pongo abelii
6044555 Culex quinquefasciatus
6995165 Cryptosporidium muris RN66
9464071 Phytophthora infestans T30-4
100194853 Salmo salar
100354833 Oryctolagus cuniculus
100407252 Callithrix jacchus
100564303 Anolis carolinensis
100604815 Nomascus leucogenys
324554 Danio rerio
495111 Xenopus laevis
51692 Homo sapiens
482962 Canis lupus familiaris
281712 Bos taurus
298916 Rattus norvegicus
54451 Mus musculus
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