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CRBN Antibodies

(Cereblon (CRBN))
This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
CRBN antibody  (AA 1-280) CRBN antibody  (AA 1-280) CRBN antibody (AA 1-280) (ABIN7165198)

CRBN Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

CRBN antibody  (AA 1-442) CRBN antibody  (AA 1-442) CRBN antibody (AA 1-442) (ABIN526543)

CRBN Reactivity: Human WB Host: Mouse Polyclonal unconjugated

CRBN antibody  (AA 35-84) CRBN antibody  (AA 35-84) CRBN antibody (AA 35-84) (ABIN6744097)

CRBN Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Horse, Monkey, Pig, Hamster, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated

CRBN Antibodies by Reactivity

Find CRBN Antibodies for a variety of species such as anti-Mouse CRBN, anti-Rat CRBN, anti-Human CRBN. The species listed below are among those available. Click on a link to go to the corresponding products.

CRBN Antibodies by Application

Find CRBN Antibodies validated for a specific application such as IF (cc), IF (p), WB, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CRBN Antibodies by Host

Find CRBN Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

CRBN Antibodies by Binding Specificity

Find CRBN Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CRBN Antibodies by Clonality

Find available monoclonal or polyclonal CRBN Antibodies. Click on a link to go to the corresponding products.

CRBN Antibodies by Conjugate

Find CRBN Antibodies with a specific conjugate such as Alexa Fluor 350, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CRBN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7165198
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN526543
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6744097
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN631784
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN2786956
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
Cat. No. ABIN1387716
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (p), IHC (fro)
Validations
Cat. No. ABIN1392919
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410807
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410808
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410809
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN1410810
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC (p), IHC (fro)
Validations
Cat. No. ABIN1410812
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN2808550
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5000487
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IF (cc), IF (p)
Validations
Cat. No. ABIN5000486
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CRBN Antibodies

Donovan, An, Nowak, Yuan, Fink, Berry, Ebert, Fischer: "Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome." in: eLife, Vol. 7, (2019) (PubMed).

Girardini, Maniaci, Hughes, Testa, Ciulli: "Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs." in: Bioorganic & medicinal chemistry, Vol. 27, Issue 12, pp. 2466-2479, (2019) (PubMed).

de Wispelaere, Du, Donovan, Zhang, Eleuteri, Yuan, Kalabathula, Nowak, Fischer, Gray, Yang: "Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations." in: Nature communications, Vol. 10, Issue 1, pp. 3468, (2019) (PubMed).

Zoppi, Hughes, Maniaci, Testa, Gmaschitz, Wieshofer, Koegl, Riching, Daniels, Spallarossa, Ciulli et al.: "Iterative design and optimization of initially inactive Proteolysis Targeting Chimeras (PROTACs) identify VZ185 as a potent, fast and selective von Hippel-Lindau (VHL)-based dual degrader probe of ..." in: Journal of medicinal chemistry, (2018) (PubMed).

Olson, Jiang, Erb, Liang, Doctor, Zhang, Zhang, Kwiatkowski, Boukhali, Green, Haas, Nomanbhoy, Fischer, Young, Bradner, Winter, Gray: "Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation." in: Nature chemical biology, Vol. 14, Issue 2, pp. 163-170, (2018) (PubMed).

Peng, Li, Clarkson, Pehar, Lao, Hillmer, Barnhart, Christian, Mitchell, Bendlin, Sandor, Puglielli: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).

Liu, Ye, Zou, Xu, Feng, Zou, Chen, Li, Cang: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, (2014) (PubMed).

Gandhi, Mendy, Waldman, Chen, Rychak, Miller, Gaidarova, Ren, Wang, Breider, Carmel, Mahmoudi, Jackson, Abbasian, Cathers, Schafer, Daniel, Lopez-Girona, Thakurta, Chopra: "Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexity." in: British journal of haematology, Vol. 164, Issue 2, pp. 233-44, (2014) (PubMed).

Charoenfuprasert, Yang, Lee, Chao, Chu, Lai, Hsu, Chang, Chen, Chen, Chang, Leu, Shih: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, (2011) (PubMed).

An, Ponthier, Sack, Seebacher, Stadler, Donovan, Fischer: "pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4CRBNubiquitin ligase." in: Nature communications, Vol. 8, pp. 15398 (PubMed).

Aliases for CRBN Antibodies

cereblon (crbn) Antibodies
cereblon (CRBN) Antibodies
ATP-dependent protease La (LON) domain protein (AT2G25740) Antibodies
cereblon (Crbn) Antibodies
2610203G15Rik Antibodies
2900045O07Rik Antibodies
AF229032 Antibodies
AW108261 Antibodies
F3N11.21 Antibodies
MRT2 Antibodies
mrt2a Antibodies
MRT2A Antibodies
piL Antibodies
zgc:92404 Antibodies
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