anti-Coenzyme Q8A (COQ8A) Antibodies

COQ8A encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. Additionally we are shipping Coenzyme Q8A Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COQ8A 56997 Q8NI60
COQ8A 67426 Q60936
COQ8A 360887 Q5BJQ0
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Top anti-Coenzyme Q8A Antibodies at antibodies-online.com

Showing 10 out of 107 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CABC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  ADCK3  Sample Type:  Thymus Tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of CABC1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of CABC1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2/mouse muscle cells, using ADCK3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB CABC1 antibody  western blot analysis in Widr cell line lysates (35ug/lane).This demonstrates the CABC1 antibody detected the CABC1 protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$335.50
Details
Human Mouse Un-conjugated IF, WB CABC1 antibody   western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CABC1  antibody detected the CABC1  protein (arrow). Confocal immunofluorescent analysis of CABC1 Antibody  with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using CABC1 Polyclonal Antibody. 100 μL Log in to see 16 Days
$181.73
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-CABC1 Antibody (C-term D531) (ABIN391179) in 293 cell line lysates (35 µg/lane). CABC1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-CABC1 Antibody (C-term) in 293 cell line lysates (35ug/lane). CABC1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details

COQ8A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Coenzyme Q8A Antibodies

  1. Human Monoclonal COQ8A Primary Antibody for ELISA, WB - ABIN528051 : OConnell, Guo, Serra, Beck, Wachtman, Hoggatt, Xia, Pearson, Knight, OConnell, Miller, Westmoreland, Bhasin: The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2015 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal COQ8A Primary Antibody for WB - ABIN2783345 : Lagier-Tourenne, Tazir, López, Quinzii, Assoum, Drouot, Busso, Makri, Ali-Pacha, Benhassine, Anheim, Lynch, Thibault, Plewniak, Bianchetti, Tranchant, Poch, DiMauro, Mandel, Barros, Hirano, Koenig: ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. in American journal of human genetics 2008 (PubMed)

More Antibodies against Coenzyme Q8A Interaction Partners

Human Coenzyme Q8A (COQ8A) interaction partners

  1. Loss of COQ8a results in cerebellar ataxia and coenzyme Q deficiency.

  2. ADCK3/COQ8 localises to mitochondrial cristae and is targeted to this organelle via the presence of an N-terminal localisation signal

  3. work reveals Mg(2 (show MUC7 Antibodies)+)-dependent ATPase (show DNAH8 Antibodies) activity of ADCK3, providing strong support for the theoretical prediction of this protein being a functional atypical kinase.

  4. a structural foundation for investigating the role of transmembrane association in regulating the biological activity of ADCK3

  5. Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.

  6. These observations highlight the importance of screening for a potentially treatable cause, CABC1/ADCK3 mutations

  7. play an important role in mediating p53 (show TP53 Antibodies)-inducible apoptosis through the mitochondrial pathway.

  8. CABC1 gene mutations in four ubiquinone-deficient patients in three distinct families were reported.

  9. Five additional mutations in ADCK3 were found in three patients with sporadic ataxia, including one known to have CoQ10 deficiency in muscle.

Mouse (Murine) Coenzyme Q8A (COQ8A) interaction partners

  1. Loss of COQ8a results in cerebellar ataxia and coenzyme Q deficiency.

Coenzyme Q8A (COQ8A) Antigen Profile

Protein Summary

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found\; however, their full-length nature has not been determined.

Gene names and symbols associated with anti-Coenzyme Q8A (COQ8A) Antibodies

  • coenzyme Q8A (COQ8A) antibody
  • coenzyme Q8A (Coq8a) antibody
  • coenzyme Q8A (coq8a) antibody
  • aarF domain containing kinase 3 (ADCK3) antibody
  • coenzyme Q8B (coq8b) antibody
  • 4632432J16Rik antibody
  • Adck3 antibody
  • adck4 antibody
  • AI462003 antibody
  • ARCA2 antibody
  • cabc1 antibody
  • COQ8 antibody
  • COQ10D4 antibody
  • mKIAA0451 antibody
  • SCAR9 antibody
  • si:dkey-114g7.2 antibody

Protein level used designations for anti-Coenzyme Q8A (COQ8A) Antibodies

aarF domain-containing protein kinase 3 , chaperone activity of bc1 complex-like, mitochondrial , chaperone, ABC1 activity of bc1 complex homolog , coenzyme Q8 homolog , chaperone, ABC1 activity of bc1 complex homolog (S. pombe) , chaperone, ABC1 activity of bc1 complex like , chaperone-ABC1-like , chaperone, ABC1 activity of bc1 complex-like , aarF domain containing kinase 3 , chaperone activity of bc1 complex-like, mitochondrial-like , atypical kinase ADCK3, mitochondrial , AarF domain-containing protein kinase 4 , CG32649-like , Coenzyme Q protein 8B , aarF domain containing kinase 4 , aarF domain-containing protein kinase 4 , atypical kinase COQ8B, mitochondrial , coenzyme Q protein 8B

GENE ID SPECIES
56997 Homo sapiens
416745 Gallus gallus
480108 Canis lupus familiaris
67426 Mus musculus
360887 Rattus norvegicus
437001 Danio rerio
536925 Bos taurus
100525602 Sus scrofa
100728070 Cavia porcellus
799071 Danio rerio
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