Coiled-Coil Domain Containing 8 Proteins (CCDC8)

CCDC8 encodes a coiled-coil domain-containing protein. Additionally we are shipping Coiled-Coil Domain Containing 8 Antibodies (47) and Coiled-Coil Domain Containing 8 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCDC8 83987 Q9H0W5
CCDC8 494320 P62521
CCDC8 434130 D3YZV8
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Top Coiled-Coil Domain Containing 8 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

CCDC8 Proteins by Origin and Source

Origin Expressed in Conjugate

Rat (Rattus)

Mouse (Murine)

More Proteins for Coiled-Coil Domain Containing 8 (CCDC8) Interaction Partners

Human Coiled-Coil Domain Containing 8 (CCDC8) interaction partners

  1. Variants near TTN (show TTN Proteins) and CCDC8 were associated with KI67 (show MKI67 Proteins) expression, and rs2288563 and rs2562832 in TTN (show TTN Proteins) are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients.

  2. CCDC8 may suppress the invasion and metastasis of non-small cell lung cancer cells.

  3. CUL7, OBSL1 and CCDC8 modulate the alternative splicing of the INSR (show INSR Proteins)

  4. The CUL7, OBSL1, and CCDC8 proteins form a 3M complex that functions in maintaining microtubule and genome integrity and normal development.

  5. Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.

  6. discussion of roles of CCDC8, CUL7 (cullin 7), and OBSL1 (obscurin-like 1) in growth and development using findings from patients with Miller-McKusick-Malvaux syndrome and Silver-Russell syndrome [REVIEW]

  7. p90 (show CANX Proteins) is a critical cofactor for p53 (show TP53 Proteins)-mediated apoptosis through promoting Tip60 (show KAT5 Proteins)-mediated p53 (show TP53 Proteins) acetylation.

  8. We propose that CUL7, OBSL1, and CCDC8 are members of a pathway controlling mammalian growth.

Coiled-Coil Domain Containing 8 (CCDC8) Protein Profile

Protein Summary

This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3).

Gene names and symbols associated with CCDC8

  • coiled-coil domain containing 8 (CCDC8)
  • coiled-coil domain containing 8 (Ccdc8)
  • 3M3 protein
  • ENSMUSG00000041117 protein
  • p90 protein
  • PPP1R20 protein

Protein level used designations for CCDC8

coiled-coil domain-containing protein 8 , protein phosphatase 1, regulatory subunit 20 , probable Coiled-coil domain-containing protein 8 , coiled-coil domain-containing protein 8 homolog

83987 Homo sapiens
494320 Rattus norvegicus
484430 Canis lupus familiaris
434130 Mus musculus
100725448 Cavia porcellus
101116079 Ovis aries
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