Coiled-Coil Domain Containing 8 Proteins (CCDC8)

CCDC8 encodes a coiled-coil domain-containing protein. Additionally we are shipping Coiled-Coil Domain Containing 8 Antibodies (47) and Coiled-Coil Domain Containing 8 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCDC8 83987 Q9H0W5
CCDC8 494320 P62521
CCDC8 434130 D3YZV8
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Top Coiled-Coil Domain Containing 8 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,626.73
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,862.83
Details

CCDC8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Rat (Rattus)

Mouse (Murine)

More Proteins for Coiled-Coil Domain Containing 8 (CCDC8) Interaction Partners

Human Coiled-Coil Domain Containing 8 (CCDC8) interaction partners

  1. Variants near TTN and CCDC8 were associated with KI67 expression, and rs2288563 and rs2562832 in TTN are potential biomarkers for the prediction of clinical outcomes in hepatitis B-related hepatocellular carcinoma patients.

  2. CCDC8 may suppress the invasion and metastasis of non-small cell lung cancer cells.

  3. CUL7, OBSL1 and CCDC8 modulate the alternative splicing of the INSR

  4. The CUL7, OBSL1, and CCDC8 proteins form a 3M complex that functions in maintaining microtubule and genome integrity and normal development.

  5. Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.

  6. discussion of roles of CCDC8, CUL7 (cullin 7), and OBSL1 (obscurin-like 1) in growth and development using findings from patients with Miller-McKusick-Malvaux syndrome and Silver-Russell syndrome [REVIEW]

  7. p90 is a critical cofactor for p53-mediated apoptosis through promoting Tip60-mediated p53 acetylation.

  8. We propose that CUL7, OBSL1, and CCDC8 are members of a pathway controlling mammalian growth.

Coiled-Coil Domain Containing 8 (CCDC8) Protein Profile

Protein Summary

This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3).

Gene names and symbols associated with CCDC8

  • coiled-coil domain containing 8 (CCDC8)
  • coiled-coil domain containing 8 (Ccdc8)
  • 3M3 protein
  • ENSMUSG00000041117 protein
  • p90 protein
  • PPP1R20 protein

Protein level used designations for CCDC8

coiled-coil domain-containing protein 8 , protein phosphatase 1, regulatory subunit 20 , probable Coiled-coil domain-containing protein 8 , coiled-coil domain-containing protein 8 homolog

GENE ID SPECIES
83987 Homo sapiens
494320 Rattus norvegicus
484430 Canis lupus familiaris
434130 Mus musculus
100725448 Cavia porcellus
101116079 Ovis aries
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