CCDC8 Products
(Coiled-Coil Domain Containing 8 (CCDC8))
Categories
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011].
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Featured CCDC8 Categories
CCDC8 Antibodies
High quality antibodies with extensive validation data.
CCDC8 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCDC8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCDC8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (3)
Cat. No.
ABIN949718
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7148148
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6260529
Quantity
100 μL
Datasheet
Datasheet
Recommended CCDC8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1773898
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1745434
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1742994
Quantity
96 tests
Datasheet
Datasheet
Recommended CCDC8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3090967
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3131096
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CCDC8 products
: "Identifying biological pathways that underlie primordial short stature using network analysis." in: Journal of molecular endocrinology, Vol. 52, Issue 3, pp. 333-44, (2014) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth." in: American journal of human genetics, Vol. 89, Issue 1, pp. 148-53, (2011) (PubMed).
: "Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 47, pp. 18937-42, (2011) (PubMed).
Synonyms and alternative names related to CCDC8
coiled-coil domain containing 8 (CCDC8), coiled-coil domain containing 8 (Ccdc8), 3M3, ENSMUSG00000041117, p90, PPP1R20Protein level used designations for CCDC8
- coiled-coil domain-containing protein 8
- protein phosphatase 1, regulatory subunit 20
- probable Coiled-coil domain-containing protein 8
- coiled-coil domain-containing protein 8 homolog
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