Collagen, Type V, alpha 2 Proteins (COL5A2)

COL5A2 encodes an alpha chain for one of the low abundance fibrillar collagens.

list all proteins Gene Name GeneID UniProt
Human COL5A2 COL5A2 1290 P05997
Mouse COL5A2 COL5A2 12832 Q3U962
Rat COL5A2 COL5A2 85250  
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Top COL5A2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$12,127.90
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Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
$437.80
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human GST tag,S tag,His tag 100 μg Log in to see 15 to 18 Days
$608.00
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Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 11 to 18 Days
$582.75
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More Proteins for Collagen, Type V, alpha 2 (COL5A2) Interaction Partners

Human Collagen, Type V, alpha 2 (COL5A2) interaction partners

  1. Mutations affecting COL5A1 or COL5A2 are responsible for spectrum of mucocutaneous, ocular and facial features in 62 classical Ehlers-Danlos syndrome patients.

  2. Bladder cancer patients in COL5A2 low expression group were associated with better invasiveness (P < .0001), tumor grade (P=.001), T staging (P < .0001), N staging (P = .002), and a trend of better M staging (P = .053) than those in COL5A2 high expression group. These results indicated that COL5A2 might promote the progression of Bladder Cancer cells.

  3. COL5A2(+/-) humans, although unlikely to present with frank classic Ehlers-Danlos syndrome, are likely to have fragile connective tissues with increased susceptibility to trauma and certain chronic pathologic conditions.

  4. data confirm that COL5A1 and COL5A2 are the major, if not the only, genes involved in classic Ehlers-danlos syndrome

  5. Col5a2 shows predictive potential in myocardial infarction , and in principle may represent a novel candidate marker for the identification and treatment of ischemic cardiovascular disease

  6. study shows that over 90% of patients, which strictly satisfy all major Villefranche criteria for classic Ehlers-Danlos Syndrome (EDS)harbor a type V collagen defect which indicates that this is the major--if not only--cause of classic EDS

  7. This study suggests a fetal association of COL5A2 and a combined fetal-maternal association of COL5A1 with spontaneous preterm delivery.

  8. Before but not after developing bronchiolitis obliterans, lung transplantation patients had antibodies to Col (show HDAC1 Proteins)-V, alpha2(V). Pep5 (show VPS11 Proteins)-8 to alpha1,2(V) and pep9-14 to alpha2(V)were immunodominant.

  9. Physical and laboratory examinations revealed that true haploinsufficiency of COL3A1 (show COL3A1 Proteins), COL5A2, and MSTN (show MSTN Proteins), but not that of SLC40A1 (show SLC40A1 Proteins), leads to a clinical phenotype.

  10. Mutations in the COL5A2 gene have been identified by DNA sequence analysis in 10 patients with spontaneous vertebral artery dissections.

Mouse (Murine) Collagen, Type V, alpha 2 (COL5A2) interaction partners

  1. Col5a2 haploinsufficiency markedly increased the incidence and severity of abdominal aortic aneurysms.

  2. Mice with null alleles for the Col5a2. Col5a2(-/-) homozygosity is embryonic lethal at approximately 12 days post conception.

  3. analysis of processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V) procollagen heterotrimer

COL5A2 Protein Profile

Protein Summary

This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.

Gene names and symbols associated with COL5A2

  • collagen type V alpha 2 chain (COL5A2)
  • collagen, type V, alpha 2a (col5a2a)
  • collagen, type V, alpha 2 (COL5A2)
  • collagen, type V, alpha 2 (Col5a2)
  • collagen type V alpha 2 chain (Col5a2)
  • 1110014L14Rik protein
  • COL5A2 protein
  • col5a2l protein
  • D230017N05 protein
  • im:7038599 protein
  • LOC100223323 protein
  • si:by143e18.1 protein
  • si:dz167c3.3 protein
  • wu:fa13f03 protein
  • wu:fa98d01 protein
  • wu:fj05e03 protein

Protein level used designations for COL5A2

alpha 2 type V collagen , collagen alpha-2(V) chain , collagen, type V, alpha 2 , collagen, type V, alpha-2 chain , collagen alpha-2(V) chain-like , AB collagen , collagen, fetal membrane, A polypeptide , type V preprocollagen alpha 2 chain , procollagen, type V, alpha 2 , collagen type V alpha 2

GENE ID SPECIES
459817 Pan troglodytes
564821 Danio rerio
282192 Bos taurus
478836 Canis lupus familiaris
100223323 Taeniopygia guttata
100457541 Pongo abelii
100472599 Ailuropoda melanoleuca
100054421 Equus caballus
100587771 Nomascus leucogenys
1290 Homo sapiens
12832 Mus musculus
85250 Rattus norvegicus
397532 Sus scrofa
423986 Gallus gallus
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