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COL19A1 encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Additionally we are shipping Collagen, Type XIX, alpha 1 Proteins (3) and Collagen, Type XIX, alpha 1 Kits (2) and many more products for this protein.
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Naturally occurring interruptions in nonfibrillar collagen play key roles in molecular flexibility, collagen degradation, and ligand binding. This study focused on a G5G type natural interruption sequence G-POALO-G from human type XIX collagen, a homotrimer collagen, as this sequence possesses distinct properties compared with those of a pathological similar Gly mutation sequence in collagen mimic peptides.
Type XIX collagen is a new partner in the interactions between tumor cells and their microenvironment. (Review)
collagen IX has unique cell adhesion properties when compared with other collagens, and it provides a novel mechanism for cell adhesion to cartilaginous matrix
The NC2 domain of collagen XIX and probably of other FACITs is responsible for chain selection and trimerization
The results of this study suggested a mechanism by which the loss of collagen XIX speeds Perineuronal Nets degradation in Telencephalon degradation.
these data not only reveal that collagen XIX is expressed by central neurons, but show for the first time that a nonfibrillar collagen is necessary for the formation of hippocampal synapses
Collagen XIX has a role in esophageal muscle development and function
This gene encodes the alpha chain of type XIX collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Although the function of this collagen is not known, other members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced.
collagen alpha-1(XIX) chain
, procollagen, type XIX, alpha 1
, collagen, type XIX, alpha 1
, alpha 1 type XIX collagen
, a1 chain of type XIX collagen
, collagen XIX, alpha-1 polypeptide
, collagen alpha 1 (Y) chain
, collagen alpha-1(Y) chain