anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Antibodies

The protein encoded by CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. Additionally we are shipping CSF3R Kits (51) and CSF3R Proteins (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CSF3R 1441 Q99062
CSF3R 12986 P40223
CSF3R 298518  
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Top anti-CSF3R Antibodies at

Showing 10 out of 194 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CSF3R Antibody (Center) (ABIN653017) in HL-60 cell line lysates (35 µg/lane). CSF3R (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma reacted with CSF3R Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow Cytometry analysis of ZR-75-1 cells using CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed, paraffin-embedded human colon carcinoma reacted with CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
Mouse Sheep APC FACS Detection of G-CSF R/CD114 in Mouse Bone Marrow by Flow Cytometry. Mouse bone marrow was stained with Rat Anti-Mouse Gr-1/Ly-6G PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
Human Mouse Un-conjugated ELISA, FACS, IHC, WB ELISA: G-CSF R/CD114 Antibody (8F8B12)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow Cytometry: G-CSF R/CD114 Antibody (8F8B12)  - Analysis of Ramos cells using CD114 mouse mAb (green) and negative control (red). 0.1 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: GCSF Receptor Antibody [NBP2-33513] - lymph node Immunohistochemistry-Paraffin: GCSF Receptor Antibody [NBP2-33513] - Immunohistochemical staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells. 0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see Available
Human Mouse Un-conjugated CyTOF, FACS, WB Detection of Human G-CSF R/CD114 by Western Blot. Western blot shows lysates of AML-193 human acute monocytic leukemia cell line. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human G-CSF R/CD114 Monoclonal Antibody. This experiment was conducted under reducing conditions. 500 μg Log in to see 8 to 9 Days
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  CSF3R  Sample Type:  293T Whole Cell lysates  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days

Top referenced anti-CSF3R Antibodies

  1. Human Polyclonal CSF3R Primary Antibody for IF (p), IHC (p) - ABIN742275 : Tajima, Waki, Tsuchiya, Hoshi et al.: Granulocyte colony-stimulating factor-producing undifferentiated carcinoma of the colon mimicking a pulmonary giant cell carcinoma: a case showing overexpression of CD44 along with highly ... in International journal of clinical and experimental pathology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CSF3R Primary Antibody for FACS - ABIN2478112 : Curtis, Patel: Pharmacy-based analytical toxicology service. in American journal of hospital pharmacy 1975 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CSF3R Primary Antibody for CyTOF, FACS - ABIN4899922 : Shao, Xu, Jing, Tweardy: Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CSF3R Primary Antibody for FACS - ABIN4896903 : Dror, Durie, Ginzberg, Herman, Banerjee, Champagne, Shannon, Malkin, Freedman: Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study. in Experimental hematology 2002 (PubMed)

  5. Human Monoclonal CSF3R Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899923 : deBruin, Lincoln, Hartley, Shehabeldin, Van, Szilvassy: Most purported antibodies to the human granulocyte colony-stimulating factor receptor are not specific. in Experimental hematology 2010 (PubMed)

  6. Mouse (Murine) Polyclonal CSF3R Primary Antibody for FACS - ABIN4896998 : Dietrich, Baryawno, Nayyar, Valtis, Yang, Ly, Besnard, Severe, Gustafsson, Andronesi, Batchelor, Sahay, Scadden: Bone marrow drives central nervous system regeneration after radiation injury. in The Journal of clinical investigation 2018 (PubMed)

More Antibodies against CSF3R Interaction Partners

Human Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. CSF3R T618I, ASXL1 G942 fs and STAT5B N642H trimutation co-contribute to a rare chronic neutrophilic leukaemia manifested by rapidly progressive leucocytosis, severe infections, persistent fever and deep venous thrombosis.

  2. expanded the regions of the CSF3R extracellular and transmembrane domains in which missense mutations exhibit leukemogenic capacity and have further elucidated the mechanistic underpinnings that underlie altered CSF3R expression, dimerization, and signaling activation

  3. Expression and role of granulocyte macrophage colony-stimulating factor receptor (GM-CSFR) and granulocyte colony-stimulating factor receptor (G-CSFR) on Ph-positive acute B lymphoblastic leukemia.

  4. we report here for the first time changes in the allele frequencies of CSF3R-T618I and SETBP1-G870S with response to ruxolitnib as well as insights into the clonal evolution of CNL under selective pressure from ruxolitinib.

  5. CSF3R genetic polymorphism occurred more frequently in the individuals with Septic Arthroplasty failure - Periprosthetic Joint Infection.

  6. G-CSF-R is C-mannosylated at W318 and that this C-mannosylation has role(s) for myeloid cell differentiation through regulating downstream signaling.

  7. CSF3R mutations co-occur with CEBPA mutations in pediatric acute myeloid leukemia.

  8. we have expanded the region of the CSF3R cytoplasmic domain in which truncation or missense mutations exhibit leukemogenic capacity, which will be useful for evaluating the relevance of CSF3R mutations in patients and helpful in defining targeted therapy strategies.

  9. our data demonstrates that E6AP facilitates ubiquitination and subsequent degradation of G-CSFR leading to attenuation of its downstream signaling and inhibition of granulocytic differentiation.

  10. study aimed to identity and characterize novel CSF3R extracellular missense mutations from exome sequencing of leukemia patients; results show the structural and functional importance of conserved extracellular cysteine pairs in CSF3R

  11. a central role of enhanced Mapk signaling in CSF3R-induced leukemia.

  12. CSF3R T618I mutation is associated with Chronic neutrophilic leukemia.

  13. biallelic CSF3R mutations were identified In the group of congenital neutropenia patients; CSF3R mutant clones are highly dynamic and may disappear and reappear during continuous granulocyte colony-stimulating factor (G-CSF) therapy. The time between the first detection of CSF3R mutations and overt leukemia is highly variable

  14. Co-occurrence of mutations in CSF3R and CEBPA in a well-defined AML subset, which uniformly responds to JAK inhibitors; this paves the way to personalized clinical trials for this disease.

  15. The quantitative methods used in this study have shown non-altered expression levels of different microglial markers (Iba-1, Cd11b and CD68), together with increased expression of IL6, IL10RA, colony stimulating factor 3 receptor and toll-like receptor 7 in the thalamus in FFI, which explains the seemingly contradictory results of the previous studies.

  16. This study proposes that acquisition of CSF3R mutations may represent a mechanism by which myeloid precursor cells carrying the ELANE mutations evade the proapoptotic activity of the Neutrophil Elastase mutants in SCN patients.

  17. CSF3R expression is significantly upregulated in human masticatory mucosa during wound healing

  18. Results indicate that granulocyte-colony stimulating factor receptor, tissue factor, and vascular endothelial growth factor receptor bound vascular endothelial growth factor expression as well as their co-expression might influence breast cancer biology.

  19. The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I

  20. CSF3R mutations, mechanisms of mutations, and their contributions to the myeloid malignancies (Review)

Mouse (Murine) Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. Anti-G-CSF receptor rapidly halted the progression of established disease in collagen Ab-induced arthritis in mice. Neutrophil accumulation in joints was inhibited, without rendering animals neutropenic, suggesting an effect of G-CSF receptor blockade on neutrophil homing to inflammatory sites.

  2. this study shows that dorsal root ganglion neurons cultured in G-CSF failed to respond to G-CSF in vitro, and Csf3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR

  3. Neutrophil activation in postischemic brain injury is regulated via upregulation of the neutrophil activator, CSFR3.

  4. Thr-615 and Thr-618 sites of membrane-proximal mutations are part of an O-linked glycosylation cluster. Mutation at these sites prevents O-glycosylation of CSF3R and increases receptor dimerization.

  5. Fbw7 together with GSK3beta negatively regulates G-CSFR expression and its downstream signaling.

  6. G-CSFR signaling interacts with retinoic acid receptors in the regulation of myeloid differentiation

  7. Expression of truncated G-CSFR significantly shortens the latency of AML in a G-CSF-dependent fashion and it is associated with a distinct AML presentation characterized by higher blast counts and more severe myelosuppression.

  8. G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance, ultimately leading to hematopoietic stem and progenitor cell mobilization.

  9. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells.

  10. murine granulocyte colony-stimulating factor receptor binds to a low molecular weight ligand

  11. Mice with truncated G-CSF receptors have neutropenia, susceptibility to infection, and bone marrow maturation arrest similar to severe congenital neutropenic humans, suggesting a role of receptor truncation mutations in SCN pathology.

  12. COOH-terminal truncation mutants of G-CSF-R, found in severe congenital neutropenia, lack internalization motifs and are completely defective in both spontaneous and ligand-induced internalization.

  13. activation of both the Flt-3 and G-CSF receptors provides a high degree of radioprotection to the hematopoietic progenitor cell and stem cell compartment.

  14. lack of negative feedback by suppressor of cytokine signaling (SOCS) proteins contribution to the signaling abnormalities of G-CSF-R mutant

  15. The tyrosine (Tyr) 729, located in the carboxy terminus of the G-CSF-R, controls the duration of G-CSF-stimulated activation of Stat5, Akt, and extracellular signal-regulated kinase 1/2.

  16. data suggested that Snapin is a new interactive protein of the granulocyte colony-stimulating factor receptor

  17. inappropriate Stat5 activation plays a key role in establishing clonal dominance by stem cells expressing mutant Csf3r.

Zebrafish Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. A severe congenital neutropenia CSF3R zebrafish deficient mutant models the human disease.

  2. GCSF/GCSFR is a conserved signaling system for facilitating the production of multiple myeloid cell lineages, as well as for early myeloid cell migration.

CSF3R Antigen Profile

Protein Summary

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Gene names and symbols associated with CSF3R

  • colony stimulating factor 3 receptor (CSF3R) antibody
  • colony stimulating factor 3 receptor (granulocyte) (Csf3r) antibody
  • colony stimulating factor 3 receptor (Csf3r) antibody
  • colony stimulating factor 3 receptor (granulocyte) (csf3r) antibody
  • colony stimulating factor 3 receptor L homeolog (csf3r.L) antibody
  • granulocyte colony-stimulating factor receptor (LOC100433338) antibody
  • cd114 antibody
  • CSF3R antibody
  • Csfgr antibody
  • G-CSF-R antibody
  • G-CSFR antibody
  • gcsfr antibody

Protein level used designations for CSF3R

CD114 antigen , G-CSF receptor , G-CSF-R , granulocyte colony-stimulating factor receptor , colony stimulating factor 3 receptor (granulocyte) , granulocyte stimulating factor receptor , granulocyte colony-stimulating factor receptor-like

1441 Homo sapiens
12986 Mus musculus
100069253 Equus caballus
298518 Rattus norvegicus
100134935 Danio rerio
446770 Xenopus laevis
419620 Gallus gallus
607605 Canis lupus familiaris
456756 Pan troglodytes
713485 Macaca mulatta
100433338 Pongo abelii
100464681 Ailuropoda melanoleuca
101118070 Ovis aries
100717194 Cavia porcellus
511511 Bos taurus
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