anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Antibodies

The protein encoded by CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. Additionally we are shipping CSF3R Kits (48) and CSF3R Proteins (26) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CSF3R 1441 Q99062
CSF3R 12986 P40223
CSF3R 298518  
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Top anti-CSF3R Antibodies at antibodies-online.com

Showing 10 out of 226 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse PE FACS Detection of G-CSF R/CD114 in Human Granulocytes by Flow Cytometry. Human granulocytes were stained with Mouse Anti-Human G-CSF R/CD114 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$328.90
Details
Human Mouse Un-conjugated CyTOF, FACS, WB Detection of Human G-CSF R/CD114 by Western Blot. Western blot shows lysates of AML-193 human acute monocytic leukemia cell line. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human G-CSF R/CD114 Monoclonal Antibody. This experiment was conducted under reducing conditions. 500 μg Log in to see 8 to 9 Days
$387.55
Details
Human Mouse Un-conjugated CyTOF, ELISA (Capture), FACS, WB Detection of Human G-CSF R/CD114 by Western Blot. Western blot shows lysates of AML-193 human acute monocytic leukemia cell line. PVDF membrane was probed with 0.5 ug/mL of Mouse Anti-Human G-CSF R/CD114 Monoclonal Antibody. This experiment was conducted under reducing conditions. 500 μg Log in to see 8 to 9 Days
$387.55
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CSF3R Antibody (Center) (ABIN653017) in HL-60 cell line lysates (35 µg/lane). CSF3R (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma reacted with CSF3R Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: G-CSF R/CD114 Antibody [NBP2-44317] - Analysis of Peripheral Blood Lymphocytes lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow Cytometry analysis of ZR-75-1 cells using CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed, paraffin-embedded human colon carcinoma reacted with CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, FACS, IHC, WB ELISA: G-CSF R/CD114 Antibody (8F8B12)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow Cytometry: G-CSF R/CD114 Antibody (8F8B12)  - Analysis of Ramos cells using CD114 mouse mAb (green) and negative control (red). 0.1 mL Log in to see 7 to 9 Days
$514.63
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$181.73
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  CSF3R  Sample Type:  293T Whole Cell lysates  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-G-CSFR/CD114 Polyclonal Antibody, Unconjugated (ABIN742275) at 1:600 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$318.45
Details

CSF3R Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CSF3R Antibodies

  1. Human Polyclonal CSF3R Primary Antibody for IF (p), IHC (p) - ABIN742275 : Tajima, Waki, Tsuchiya, Hoshi et al.: Granulocyte colony-stimulating factor-producing undifferentiated carcinoma of the colon mimicking a pulmonary giant cell carcinoma: a case showing overexpression of CD44 along with highly ... in International journal of clinical and experimental pathology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CSF3R Primary Antibody for FACS - ABIN2478112 : Curtis, Patel: Pharmacy-based analytical toxicology service. in American journal of hospital pharmacy 1975 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CSF3R Primary Antibody for CyTOF, FACS - ABIN4899922 : Shao, Xu, Jing, Tweardy: Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CSF3R Primary Antibody for FACS - ABIN4896903 : Dror, Durie, Ginzberg, Herman, Banerjee, Champagne, Shannon, Malkin, Freedman: Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study. in Experimental hematology 2002 (PubMed)

  5. Human Monoclonal CSF3R Primary Antibody for CyTOF, ELISA (Capture) - ABIN4899923 : deBruin, Lincoln, Hartley, Shehabeldin, Van, Szilvassy: Most purported antibodies to the human granulocyte colony-stimulating factor receptor are not specific. in Experimental hematology 2010 (PubMed)

  6. Human Polyclonal CSF3R Primary Antibody for ELISA, WB - ABIN4313030 : Meenhuis, Verwijmeren, Roovers, Touw: The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor. in The Biochemical journal 2011 (PubMed)

More Antibodies against CSF3R Interaction Partners

Human Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. G-CSF-R is C-mannosylated at W318 and that this C-mannosylation has role(s) for myeloid cell differentiation through regulating downstream signaling.

  2. CSF3R mutations co-occur with CEBPA (show CEBPA Antibodies) mutations in pediatric acute myeloid leukemia (show BCL11A Antibodies).

  3. we have expanded the region of the CSF3R cytoplasmic domain in which truncation or missense mutations exhibit leukemogenic capacity, which will be useful for evaluating the relevance of CSF3R mutations in patients and helpful in defining targeted therapy strategies.

  4. our data demonstrates that E6AP (show ube3a Antibodies) facilitates ubiquitination and subsequent degradation of G-CSFR leading to attenuation of its downstream signaling and inhibition of granulocytic differentiation.

  5. study aimed to identity and characterize novel CSF3R extracellular missense mutations from exome sequencing of leukemia patients; results show the structural and functional importance of conserved extracellular cysteine pairs in CSF3R

  6. a central role of enhanced Mapk (show MAPK1 Antibodies) signaling in CSF3R-induced leukemia.

  7. CSF3R T618I mutation is associated with Chronic neutrophilic leukemia.

  8. biallelic CSF3R mutations were identified In the group of congenital neutropenia patients; CSF3R mutant clones are highly dynamic and may disappear and reappear during continuous granulocyte colony-stimulating factor (G-CSF (show CSF3 Antibodies)) therapy. The time between the first detection of CSF3R mutations and overt leukemia is highly variable

  9. Co-occurrence of mutations in CSF3R and CEBPA (show CEBPA Antibodies) in a well-defined AML (show RUNX1 Antibodies) subset, which uniformly responds to JAK (show JAK3 Antibodies) inhibitors; this paves the way to personalized clinical trials for this disease.

  10. The quantitative methods used in this study have shown non-altered expression levels of different microglial markers (Iba-1 (show AIF1 Antibodies), Cd11b (show ITGAM Antibodies) and CD68 (show CD68 Antibodies)), together with increased expression of IL6 (show IL6 Antibodies), IL10RA (show IL10RA Antibodies), colony stimulating factor (show CSF2 Antibodies) 3 receptor and toll-like receptor 7 (show TLR7 Antibodies) in the thalamus in FFI, which explains the seemingly contradictory results of the previous studies.

Mouse (Murine) Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. Anti-G-CSF receptor rapidly halted the progression of established disease in collagen Ab-induced arthritis in mice. Neutrophil accumulation in joints was inhibited, without rendering animals neutropenic, suggesting an effect of G-CSF receptor blockade on neutrophil homing to inflammatory sites.

  2. this study shows that dorsal root ganglion neurons cultured in G-CSF (show CSF3 Antibodies) failed to respond to G-CSF (show CSF3 Antibodies) in vitro, and Csf3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR

  3. Thr (show TRH Antibodies)-615 and Thr (show TRH Antibodies)-618 sites of membrane-proximal mutations are part of an O-linked glycosylation cluster. Mutation at these sites prevents O-glycosylation of CSF3R and increases receptor dimerization.

  4. Fbw7 (show FBXW7 Antibodies) together with GSK3beta negatively regulates G-CSFR expression and its downstream signaling.

  5. G-CSFR signaling interacts with retinoic acid receptors in the regulation of myeloid differentiation

  6. Expression of truncated G-CSFR significantly shortens the latency of AML (show RUNX1 Antibodies) in a G-CSF (show CSF3 Antibodies)-dependent fashion and it is associated with a distinct AML (show RUNX1 Antibodies) presentation characterized by higher blast counts and more severe myelosuppression.

  7. G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance, ultimately leading to hematopoietic stem and progenitor cell mobilization.

  8. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF (show CSF3 Antibodies)-induced expansion of myeloid progenitor cells.

  9. murine granulocyte colony-stimulating factor receptor binds to a low molecular weight ligand

  10. Mice with truncated G-CSF (show CSF3 Antibodies) receptors have neutropenia, susceptibility to infection, and bone marrow maturation arrest similar to severe congenital neutropenic humans, suggesting a role of receptor truncation mutations in SCN (show SRI Antibodies) pathology.

Zebrafish Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. GCSF (show CSF3 Antibodies)/GCSFR is a conserved signaling system for facilitating the production of multiple myeloid cell lineages, as well as for early myeloid cell migration.

CSF3R Antigen Profile

Protein Summary

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Gene names and symbols associated with CSF3R

  • colony stimulating factor 3 receptor (CSF3R) antibody
  • colony stimulating factor 3 receptor (granulocyte) (Csf3r) antibody
  • colony stimulating factor 3 receptor (Csf3r) antibody
  • colony stimulating factor 3 receptor (granulocyte) (csf3r) antibody
  • colony stimulating factor 3 receptor L homeolog (csf3r.L) antibody
  • granulocyte colony-stimulating factor receptor (LOC100433338) antibody
  • cd114 antibody
  • CSF3R antibody
  • Csfgr antibody
  • G-CSF-R antibody
  • G-CSFR antibody
  • gcsfr antibody

Protein level used designations for CSF3R

CD114 antigen , G-CSF receptor , G-CSF-R , granulocyte colony-stimulating factor receptor , colony stimulating factor 3 receptor (granulocyte) , granulocyte stimulating factor receptor , granulocyte colony-stimulating factor receptor-like

GENE ID SPECIES
1441 Homo sapiens
12986 Mus musculus
100069253 Equus caballus
298518 Rattus norvegicus
100134935 Danio rerio
446770 Xenopus laevis
419620 Gallus gallus
607605 Canis lupus familiaris
456756 Pan troglodytes
713485 Macaca mulatta
100433338 Pongo abelii
100464681 Ailuropoda melanoleuca
101118070 Ovis aries
100717194 Cavia porcellus
511511 Bos taurus
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