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May regulate the number of excitatory synapses that are formed on hippocampus neurons.
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Data identify C1QL3 as a signaling molecule that is highly expressed in suprachiasmatic nucleus neurons, where it contributes to the formation and/or maintenance of glutamatergic synapses and plays a role in circadian behaviors, which may include circadian aftereffects.
results suggest that C1ql3 is a signaling protein essential for subsets of synaptic projections and the behaviors controlled by these projections.
CTRP13 and AgRP (show AGRP Proteins) form a hypothalamic feedback loop to modulate food intake
CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase (show G6PC Proteins) and the cytosolic form of phosphoenolpyruvate carboxykinase (show PEPCK Proteins).
CTRP13 is a novel adipokine that is down-regulated in the serum of type 2 diabetics.
decreased levels of CTRP3 and especially CTRP13 were associated with increased risk of T2DM and CAD
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).
C1q and tumor necrosis factor-related protein 13
, C1q/TNF-related protein 13
, complement C1q-like protein 3