Complement Component 3a Receptor 1 (C3AR1) ELISA Kits

Zebrafish Complement Component 3a Receptor 1 (C3AR1) interaction partners

1. Neural crest cells are coattracted via the complement fragment C3a (show C3 ELISA Kits) and its receptor C3aR, revealing an unexpected role of complement proteins in early vertebrate development.

Human Complement Component 3a Receptor 1 (C3AR1) interaction partners

1. Studies indicate that the complement response lie the active fragments, C3a (show C3 ELISA Kits) and C5a, acting through their specific receptors, C3aR, C5aR1 (show C5AR1 ELISA Kits) and C5aR2 to direct the cellular response to inflammation.

2. High C3aR1 expression is associated with acute myeloid leukemia (show BCL11A ELISA Kits)-M2.

3. these findings suggest a critical role for C3a (show C3 ELISA Kits) through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

4. Medulloblastoma cells express C3aR, and siRNA-mediated knockdown of C3aR inhibits proliferation of these cells in vitro.

5. Observed a positive correlation between the expression of anaphylatoxin-receptors C3aR and C5aR (show C5AR1 ELISA Kits) with platelet activation in patients with coronary artery disease.

6. The obesity-induced down-regulation of complement C3 (show C3 ELISA Kits) and C3aR which is specific to subcutaneous adipose tissue.

7. In patients with IgAN, urinary and renal C3a (show C3 ELISA Kits) and C5a and renal expression of C3aR and C5aR (show C5AR1 ELISA Kits) are significantly correlated with the activity and severity of renal injury.

8. C3aR and CD46 (show CD46 ELISA Kits) activation via intrinsic generation of their respective ligands is an integral part of human Th1 (show TH1L ELISA Kits) (but not Th2) immunity.

9. functional regulation of C3aR by NHERFs in human mast cells

10. significantly decreased expression of C3aR mRNA and protein expression in placentas with preeclampsia compared to controls

Mouse (Murine) Complement Component 3a Receptor 1 (C3AR1) interaction partners

1. Complement component 3a receptor 1 role in the lung cancer progression.

2. The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP-21.

3. whilst the C3aR modulates some elements of disease pathogenesis, overall it is not critical in effector responses and glomerular injury caused by autoimmunity to MPO (show MPO ELISA Kits)

4. study provided detailed insights into the C3aR expression pattern in immune and stromal cells under steady-state conditions

5. proposal that C3aR activation alters the tumor inflammatory milieu, thereby promoting tumor growth

6. The roles of C3, CfB (show CFB ELISA Kits), and C3a (show C3 ELISA Kits) receptor in the severity of S. aureus induced septic arthritis are reported.

7. increased circulating lipopolysaccharide induces upregulation of complement C3a (show C3 ELISA Kits) receptor on neutrophils and activation of the complement cascade.

8. showed that C3a (show C3 ELISA Kits) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods

9. these findings suggest a critical role for C3a (show C3 ELISA Kits) through autocrine/paracrine induction of C3aR in the pathogenesis of cigarette smoke-induced sterile inflammation and provide new therapeutic targets for the treatment of emphysema.

10. C3a (show C3 ELISA Kits)/C3aR signaling during host immune response suppresses Fas (show FAS ELISA Kits) expression and caspase-3 (show CASP3 ELISA Kits) activity while increasing Bcl-2 (show BCL2 ELISA Kits) proto-oncogene (show RAB1A ELISA Kits) protein expression, providing protection to myeloid and lymphoid cells against L. monocytogenes-induced apoptosis.