Complement Factor H-Related 1 Proteins (CFHR1)

CFHR1 encodes a secreted protein belonging to the complement factor H protein family. Additionally we are shipping CFHR1 Antibodies (44) and CFHR1 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse CFHR1 CFHR1 50702  
Rat CFHR1 CFHR1 289057  
CFHR1 3078 Q03591
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Top CFHR1 Proteins at

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
Human Human His tag   10 μg Log in to see 15 to 16 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human His tag   10 μg Log in to see 12 to 15 Days

CFHR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,

More Proteins for Complement Factor H-Related 1 (CFHR1) Interaction Partners

Human Complement Factor H-Related 1 (CFHR1) interaction partners

  1. To our knowledge, this is the first evaluation of the involvement of the CFHR3/CFHR1 deletion and age-related macular degeneration in CFH (show CFH Proteins) Y402H polymorphism Brazilian patients.

  2. These results identify C-reactive protein (show CRP Proteins) as a ligand for FHR-1 and suggest that FHR-1 enhances, rather than inhibits, complement activation, which may explain the protective effect of FHR-1 deficiency in age-related macular degeneration.

  3. The CFHR1 level in plasma of T2DM patients were significantly higher than that of the healthy controls.

  4. CFHL-1 is a CFH (show CFH Proteins) gene splice variant.

  5. We investigated whether the causal sequence variant resides in the CFH (show CFH Proteins) gene or the neighboring complement factor H-related 1 (CFHR1) gene, and fine mapping Implicates a deletion of CFHR1 in protection from IgA nephropathy in Han Chinese

  6. Next-generation sequencing of the CFH (show CFH Proteins) region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH (show CFH Proteins)-related genes in the retina or RPE (show RPE Proteins)/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR1]

  7. Studies indicate that complement factor H (show CFH Proteins)-related proteins (FHR1-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  8. These results suggest that the combination of quantitative and qualitative variations in the complement proteins encoded by CFH (show CFH Proteins), CFHR3 and CFHR1 genes is key for the association of these haplotypes with disease.

  9. Genetic variants in CFH, CFHR3, and CFHR1 affect complement activation and thereby predispose patients to develop IgA nephropathy.

  10. An average of 15.2% of factor H (show CFH Proteins)-autoantibody positive individuals with rheumatic diseases or hemolytic uremic syndrome had homozygous deficiency of CFHR1.

CFHR1 Protein Profile

Protein Summary

This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

Gene names and symbols associated with CFHR1

  • complement factor H-related 1 (Cfhr1)
  • complement factor H-related protein 1 (LOC735590)
  • complement factor H-related protein 1 (LOC746429)
  • complement factor H related 1 (CFHR1)
  • AI194696 protein
  • CFHL protein
  • CFHL1 protein
  • CFHL1P protein
  • CFHR1P protein
  • CFHRB protein
  • FHR1 protein
  • H36-1 protein
  • H36-2 protein
  • HFL1 protein
  • HFL2 protein

Protein level used designations for CFHR1

complement component factor h-like 1 , complement factor H-related protein , complement factor H-related protein 1 , complement factor H-related 1 , FHR-1 , H factor (complement)-like 1 , H factor (complement)-like 2 , H-factor-like 1 , H36 , complement factor H-related 1 pseudogene , h factor-like protein 1

50702 Mus musculus
289057 Rattus norvegicus
735590 Pan troglodytes
746429 Pan troglodytes
3078 Homo sapiens
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