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CFHR1 Protein (His tag)

CFHR1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319271
  • Target See all CFHR1 Proteins
    CFHR1 (Complement Factor H-Related 1 (CFHR1))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CFHR1 protein is labelled with His tag.
    Purpose
    Recombinant Human CFHR1 Protein (His Tag)
    Sequence
    Glu19-Arg330
    Characteristics
    Recombinant Human Complement Factor H-Related 1 is produced by our Mammalian expression system and the target gene encoding Glu19-Arg330 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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    Discover our top product CFHR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl,2 mM EDTA, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CFHR1 (Complement Factor H-Related 1 (CFHR1))
    Alternative Name
    CFHR1 (CFHR1 Products)
    Synonyms
    AI194696 Protein, CFHRB Protein, Cfhl1 Protein, CFHL Protein, CFHL1 Protein, CFHL1P Protein, CFHR1P Protein, FHR1 Protein, H36-1 Protein, H36-2 Protein, HFL1 Protein, HFL2 Protein, complement factor H-related 1 Protein, complement factor H-related protein 1 Protein, complement factor H related 1 Protein, Cfhr1 Protein, LOC735590 Protein, LOC746429 Protein, CFHR1 Protein
    Background

    Background: Complement Factor H-Related 1 (CFHR1) is a 43 kDa secreted member of the factor H family of glycoproteins. The human Complement Factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1 (FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. FHR1 is produced by hepatocytes and circulates as two differentially glycosylated isoforms (37 kDa and 43 kDa). Mature human FHR1 is 312 amino acids in length. It contains five, approximately 60 aa SCRs that basically constitute the entire molecule. FHR1 may play a role in complement regulation, lipid metabolism and lipoprotein complexes that bind PMNs to LPS.

    Synonym: Complement Factor H-Related Protein 1, FHR-1, H Factor-Like Protein 1, H-Factor-Like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2

    Molecular Weight
    36.8 kDa
    UniProt
    Q03591
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