anti-Complement Factor H-Related 3 (CFHR3) Antibodies

The protein encoded by CFHR3 is a secreted protein, which belongs to the complement factor H-related protein family. Additionally we are shipping CFHR3 Kits (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse CFHR3 CFHR3 624286  
CFHR3 10878 Q02985
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Top anti-CFHR3 Antibodies at

Showing 8 out of 9 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cells, using CFHR3 antibody. Immunofluorescence analysis of A549 cell using CFHR3 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of FHR3 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Western blot analysis of FHR3 expression in A549 (A), HepG2 (B), NIH3T3 (C), mouse liver (D), rat liver (E) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Horse Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   50 μL Log in to see 13 to 16 Days
Human Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   50 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated   50 μL Log in to see 11 to 16 Days
Human Rabbit Un-conjugated IF/ICC, IHC, WB   100 μL Log in to see 11 to 16 Days

CFHR3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Horse (Equine)

More Antibodies against CFHR3 Interaction Partners

Human Complement Factor H-Related 3 (CFHR3) interaction partners

  1. To our knowledge, this is the first evaluation of the involvement of the CFHR3/CFHR1 (show CFHR1 Antibodies) deletion and age-related macular degeneration in CFH (show CFH Antibodies) Y402H polymorphism Brazilian patients.

  2. These data provide evidence that FHR3, which is absent in patients with the autoimmune form of hemolytic uremic syndrome, is involved in B cell regulation

  3. We describe a novel CFH (show CFH Antibodies)/CFHR3 hybrid gene secondary to a de novo 6.3-kb deletion that arose through microhomology-mediated end joining rather than nonallelic homologous recombination. We confirmed a transcript from this hybrid gene and showed a secreted protein product that lacks the recognition domain of factor H (show CFH Antibodies) and exhibits impaired cell surface complement regulation

  4. Next-generation sequencing of the CFH (show CFH Antibodies) region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH (show CFH Antibodies)-related genes in the retina or RPE (show RPE Antibodies)/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins.[CFHR3]

  5. Studies indicate that complement factor H (show CFH Antibodies)-related proteins (FHR1 (show CFHR1 Antibodies)-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  6. These results suggest that the combination of quantitative and qualitative variations in the complement proteins encoded by CFH (show CFH Antibodies), CFHR3 and CFHR1 (show CFHR1 Antibodies) genes is key for the association of these haplotypes with disease.

  7. Genetic variants in CFH, CFHR3, and CFHR1 affect complement activation and thereby predispose patients to develop IgA nephropathy.

  8. Prompt use of immunosuppressive agents and plasma exchanges are useful for improving outcomes in pediatric patients with anti-complement factor H (show CFH Antibodies)-associated HUS (show CFH Antibodies).

  9. Atypical haemolytic-uraemic syndrome due to heterozygous mutations of CFH (show CFH Antibodies)/CFHR1 (show CFHR1 Antibodies)-3 and complement factor H (show CFH Antibodies) 479.

  10. we have assessed the relationship between GA and previously identified AMD (show AMD1 Antibodies)-associated variants of genes (CFH (show CFH Antibodies), CFB (show CFB Antibodies), C3, FHR1 (show CFHR1 Antibodies), FRH3, and ARMS2 (show ARMS2 Antibodies)/HTRA (show HTRA1 Antibodies)).

CFHR3 Antigen Profile

Protein Summary

The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CFHR3

  • complement factor H-related 3 (Cfhr3) antibody
  • complement factor H related 3 (CFHR3) antibody
  • CFHL3 antibody
  • DOWN16 antibody
  • EG624286 antibody
  • FHR-3 antibody
  • FHR3 antibody
  • HLF4 antibody

Protein level used designations for CFHR3

H factor-like 4 , H factor-like protein 3 , complement factor H-related protein 3

624286 Mus musculus
10878 Homo sapiens
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