CFHR3 antibody (Middle Region)

Catalog No. ABIN5517788

The Rabbit Polyclonal anti-CFHR3 antibody (ABIN5517788) specifically detects CFHR3 in WB. The antibody is reactive with Human, Rat and Horse samples.

Quick Overview for CFHR3 antibody (Middle Region) (ABIN5517788)

Target: CFHR3 (Complement Factor H-Related 3 (CFHR3))

Reactivity: Human, Rat, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CFHR3 Antibody

Binding Specificity: Middle Region

Purpose: CFHR3 Antibody - middle region

Sequence: FISESSSIYI LNKEIQYKCK PGYATADGNS SGSITCLQNG WSAQPICINS

Predicted Reactivity: Horse: 79%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against FHR3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FHR3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52394-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CFHR3

Target: CFHR3 (Complement Factor H-Related 3 (CFHR3))

Alternative Name: CFHR3

Background:

Background Information: The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: complement factor H related 3

Alternative Symbols: FHR3, HLF4, CFHL3, FHR-3, DOWN16

Protein Name: complement factor H-related protein 3

Molecular Weight: 36kDa

Gene ID: 10878

NCBI Accession: NP_066303

UniProt: Q02985