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CPNE6 encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. Additionally we are shipping CPNE6 Antibodies (61) and many more products for this protein.
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we identify copine-6 as a specific regulator of spontaneous neurotransmission
links activity-triggered calcium signals to spine structural plasticity necessary for learning and memory
The second C2-domain of copine-6 is responsible for calcium-dependent membrane association.
expression of CPNE6 increased remarkably in brains of epileptic patients and in experimental epileptic rats. Expression is mainly in neurons.
This gene encodes a brain-specific member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains, and one von Willebrand factor A domain. It may have a role in synaptic plasticity.
, copine VI (neuronal)
, neuronal copine