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The protein encoded by CDK20 contains a kinase domain most closely related to the cyclin-dependent protein kinases. Additionally we are shipping Cyclin-Dependent Kinase 20 Proteins (12) and Cyclin-Dependent Kinase 20 Kits (1) and many more products for this protein.
Showing 10 out of 104 products:
Human Monoclonal CDK20 Primary Antibody for WB - ABIN1882214
Wang, Kung: Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1. in Oncogene 2012
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Human Monoclonal CDK20 Primary Antibody for WB - ABIN1882215
Liu, Wu, Galaktionov: p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells. in The Journal of biological chemistry 2004
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Results delineate an immunosuppressive mechanism of the hepatoma-intrinsic CCRK signalling and highlight an overexpressed kinase target whose inhibition might empower hepatocellular carcinoma immunotherapy
A CCRK-EZH2 (show EZH2 Antibodies) epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patient.
In glioblastoma cells with deregulated high levels of CCRK, its depletion restores cilia through ICK (show ICK Antibodies) and an ICK (show ICK Antibodies)-related kinase MAK (show MAK Antibodies), thereby inhibiting glioblastoma cell proliferation.
Data indicate that expression of ERAS, LHX1 (show LHX1 Antibodies), and CCRK is increased in aggressive subgroups of medulloblastomas.
Cell cycle-related kinase is a direct androgen receptor (show AR Antibodies)-regulated gene that drives beta-catenin (show CTNNB1 Antibodies)/T cell factor-dependent hepatocarcinogenesis
results suggest for the first time that CCRK is involved in colorectal cancer carcinogenesis and G1/S cell cycle transition by regulating Cdk2 (show CDK2 Antibodies), cyclin E (show CCNE1 Antibodies) and Rb.
identification of p42 (show EPB42 Antibodies), a novel cyclin-dependent kinase (show CDK1 Antibodies)-activating kinase (CAK (show CCNH Antibodies)) activity in human cells; p42 (show EPB42 Antibodies) is essential for the phosphorylation of Thr (show TRH Antibodies)-160 and activation of CDK2 (show CDK2 Antibodies) and is indispensable for cell growth
Depletion of PNQALRE by >80% due to RNA interference (RNAi) impairs cell proliferation, but fails to arrest the cell cycle at a discrete point.
Overexpression of CCRK is associated with ovarian carcinoma.
heart expresses a splice variant of CCRK, which promotes cardiac cell growth and survival; differs from the generic isoform in protein-protein interactions, substrate specificity and regulation of cell cycle; and is down-regulated in heart failure
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
, CDK-activating kinase p42
, cell cycle-related kinase
, cell division protein kinase 20
, cyclin-dependent protein kinase H
, cyclin-kinase-activating kinase p42
, cell cycle related kinase
, cell cycle-related kinase cardiac
, CDK-related protein kinase PNQLARE
, cyclin-dependent kinase 20
, LOW QUALITY PROTEIN: cyclin-dependent kinase 20