Cysteinyl Leukotriene Receptor 2 (CYSLTR2) ELISA Kits

Human Cysteinyl Leukotriene Receptor 2 (CYSLTR2) interaction partners

1. our study identifies CYSLTR2 L129Q alterations as a previously unrecognized activating mutation in blue nevi, occuring in a mutually exclusive fashion with known GNAQ (show GNAQ ELISA Kits) and GNA11 (show GNA11 ELISA Kits) mutations.

2. The expression of CysLTR1 (show CYSLTR1 ELISA Kits) and CysLTR2 is higher in the lymphocytes of hyperplasic tonsils in nonallergic children

3. findings implicate CYSLTR2 as a uveal melanoma oncogene (show RAB1A ELISA Kits) and highlight the critical role of Galphaq (show GNAQ ELISA Kits) signaling in uveal melanoma pathogenesis

4. CysLT2 receptors were expressed in lung specimens isolated from asthma subjects. Activation of CysLT2 receptors may contribute to antigen-induced bronchoconstriction in certain asthma population.

5. CysLTR-1 (show CYSLTR1 ELISA Kits) and CysLTR-2 are highly expressed in the adenoid tissues from children with AH, suggesting that leukotrienes are involved in the pathogenesis of AH.

6. Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.

7. ATRA treatment induces CysLT(2)R mRNA and protein expression in colon cancer cell lines

8. CysLT2 receptor plays a primary role in the vascular responses in the upper respiratory tract.

9. There is a protective role against tumor progression for CysLT(2)R and that it highlights new possibilities to regulate the CysLT(2)R.

10. The synthesis of cys (show DNAJC5 ELISA Kits)-LTs from LTA (show LTA ELISA Kits)(4) by endothelial cells is directly associated with the activation of the CysLT(2) receptor in a typical autocrine fashion.

Mouse (Murine) Cysteinyl Leukotriene Receptor 2 (CYSLTR2) interaction partners

1. CysLT2R signaling, IL-33 (show IL33 ELISA Kits)-dependent group 2 innate lymphoid cell expansion, and IL-33 (show IL33 ELISA Kits)-driven mast cell activation are necessary for induction of type 2 immunopathology and aspirin sensitivity. CysLT2R-targeted drugs may interrupt these processes.

2. The CysLT(1 (show CYSLTR1 ELISA Kits)) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils

3. Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.

4. LTC4 activates mouse platelets exclusively through CysLT2R. LTC4/CysLT2R signaling required an autocrine ADP-mediated response through P2Y12 (show P2RY12 ELISA Kits) receptors.

5. CysLT1R (show CYSLTR1 ELISA Kits), CysLT2R and GPR17 might be involved in the MPTP (show PTPN2 ELISA Kits)-induced Parkinson disease damage in mice.

6. CysLT2R negatively regulates the development of cys (show DNAJC5 ELISA Kits)-LT-dependent T helper cell (Th)2 pulmonary inflammation by inhibiting both CysLT1R (show CYSLTR1 ELISA Kits) signaling and house dust mite-induced LTC4S (show LTC4S ELISA Kits)-dependent cell surface expression of CysLT1R (show CYSLTR1 ELISA Kits) on dendritic cells.

7. These findings establish a role for eosinophil-derived cysteinyl leukotriene and the CysLT(2)R in the hyperkeratosis and fibrosis of allergic skin inflammation.

8. Results implicate the CysLT(2)R in the progression of ischemic retinopathy.

9. These results suggest that a lack of neuronal expression of CysLTR (show CYSLTR1 ELISA Kits) in the murine colonic myenteric plexus attenuates colitis disease progression.

10. findings show that CysLT1 receptor (show CYSLTR1 ELISA Kits) attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death

Cow (Bovine) Cysteinyl Leukotriene Receptor 2 (CYSLTR2) interaction partners

1. In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase (show ALOX5 ELISA Kits)) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase (show LTC4S ELISA Kits)) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 (show PTGR1 ELISA Kits) level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows.