Cytochrome B-245, beta Polypeptide (CYBB) ELISA Kits

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Additionally we are shipping CYBB Antibodies (133) and CYBB Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYBB 1536 P04839
CYBB 13058 Q61093
CYBB 66021  
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Top CYBB ELISA Kits at antibodies-online.com

Showing 5 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Mouse 11.75 pg/mL 47-3000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat 0.057 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$800.00
Details
Human < 0.055 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Rat < 0.057 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$867.02
Details

Top referenced CYBB ELISA Kits

  1. Rat (Rattus) CYBB ELISA Kit for Sandwich ELISA - ABIN433568 : Du, Wang, Wang: Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome. in Graefe's archive for clinical and experimental ophthalmology 2016 (PubMed)

  2. Human CYBB ELISA Kit for Sandwich ELISA - ABIN418998 : Tassone, Perticone, Sciacqua, Mafrici, Settino, Malara, Mollace, Sesti, Perticone: Low dose of acetylsalicylic acid and oxidative stress-mediated endothelial dysfunction in diabetes: a short-term evaluation. in Acta diabetologica 2015 (PubMed)

More ELISA Kits for CYBB Interaction Partners

Zebrafish Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. The nox1 (show NOX1 ELISA Kits), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization

Rabbit Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that NADPH oxidase (show NOX1 ELISA Kits) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.

Human Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. To further elucidate the mAb 7D5 epitope on human gp91(phox) , chimeric DNA expressed human and mouse gp91(phox) recombinant protein were constructed. The fusion proteins were immunostained for mAb 7D5 and analyzed by FACS and western blot analysis.

  2. Phorbol 12-myristate-13-acetate-stimulated NOX2-NIS (NOX-specific Insertion Sequence) phosphorylation by ATM (show ATM ELISA Kits) kinase causes a dynamic switch that deactivates NOX2 activity. This downregulation may be defective in NOX2-NIS3 mutant because of the absence of Ser486.

  3. This study identifies one novel mutation in the IL2RG (show IL2RG ELISA Kits) gene and another, previously described mutation in the CYBB genes. It is the first report establishing a diagnosis of X-SCID (show PRKDC ELISA Kits) and X-CGD using WES in Chinese patients.

  4. In a male patient suffering from X-linked chronic granulomatous disease (CGD) we found a c.389G>T mutation in exon 5 of the CYBB gene.

  5. The potency of RTK inhibition by BJ-1301 was lower than that of sunitinib (a multi-RTK inhibitor), but the inhibition of downstream signaling pathways (e.g., ROS (show ROS1 ELISA Kits) generation) and subsequent biological changes (e.g., NOX2 induction) by BJ-1301 was superior

  6. Translated to human pathophysiology, (show ALDH2 ELISA Kits)we found increased gp91(phox) expression in endomyocardial biopsies of Alcoholic cardiomyopathy (ACM) patients. In conclusion, ACM is promoted by ACA-driven mitochondrial dysfunction and can be improved by ablation of NOX2/gp91(phox). NOX2/gp91(phox) therefore might be a potential pharmacological target to treat ACM.

  7. We demonstrated that small interfering RNA (siRNA)-mediated knockdown of PRR (show PVRL1 ELISA Kits), Nox2 and Nox4 (show NOX4 ELISA Kits) significantly reduced the HG-induced stimulation of VEGF (show VEGFA ELISA Kits). On the other hand, Nox4 (show NOX4 ELISA Kits) overexpression significantly potentiated PRR (show PVRL1 ELISA Kits)-induced stimulation of VEGF (show VEGFA ELISA Kits) under hyperglycemia in ARPE-19 cells.

  8. NOX2 isoform in blood samples has been considered as biomarker of disease severity and treatment efficacy in neurodegenerative disease. (Review)

  9. Study demonstrates that there is no increase of NOX2 expression in schizophrenic patients. Unexpectedly, however, the study found that NOX2 expression was decreased in patients with bipolar disorder.

  10. Hyperinsulinemia modulates arteriolar flow-induced dilation via Nox2-mediated superoxide production.

Cow (Bovine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that the efficiency of NADPH oxidase (show NOX1 ELISA Kits) enzymatic activity is higher at endoplasmic reticulum (ER).

  2. A p47(phox) and Src kinase (show CSK ELISA Kits) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC ELISA Kits)

Mouse (Murine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Whereas the oxidative burst in myeloid cells is mainly catalyzed by the NOX2 isotype, in epithelial cells other isotypes of the NADPH (show FDXR ELISA Kits) oxidases family are involved, especially NOX4 (show NOX4 ELISA Kits)

  2. Proximal point of bifurcation in cardiac insulin (show INS ELISA Kits) signaling through the simultaneous activation of both NOX2 and NOX4 (show NOX4 ELISA Kits) was identified. Each NOX isoform generates H2O2 in cardiac myocytes with distinct time courses, with H2O2 derived from NOX2 augmenting Akt (show AKT1 ELISA Kits)-dependent metabolic effects of insulin (show INS ELISA Kits), while H2O2 from NOX4 (show NOX4 ELISA Kits) blocks beta adrenergic increases in inotropy.

  3. AIF (show AIFM1 ELISA Kits) activated AMPK (show PRKAA1 ELISA Kits)-dependent Nox2 signaling pathway.

  4. Nox2 may be a therapeutic target for AII (show ARG2 ELISA Kits)-induced skeletal muscle atrophy.

  5. These results indicated that integrin CD11b (show ITGAM ELISA Kits) mediates alpha-synuclein-induced NOX2 activation through a RhoA (show RHOA ELISA Kits)-dependent pathway.

  6. These results showed that CR3 (show ITGAM ELISA Kits) regulated Nox2 activation and dopaminergic neurodegeneration through a Src (show SRC ELISA Kits)-Erk (show EPHB2 ELISA Kits)-dependent pathway in a two pesticide-induced Parkinson's disease (PD) model, providing novel insights into the immune pathogenesis of PD.

  7. High levels of NOX2 were found in mouse adult neurogenic brain regions. NOX2-deficient brain showed decrease in neuroprecursor cell pool and lowered expression of genes involved in neural differentiation.

  8. Echocardiography revealed that ALDH-2 (show ALDH2 ELISA Kits)(-/-)/gp91(phox-/-) mice were protected from ACA-overload-induced HF after 5 weeks of 2% EtOH-diet, demonstrating that NOX2-derived O2(*-) contributes to the development of ACM

  9. Nox2 activation favors thioredoxin-1 (TRX-1 (show TXN ELISA Kits))/p40phox interaction, which leads to exclusion of TRX-1 (show TXN ELISA Kits) from the nucleus.

  10. these observations indicate that Nox2-mediated ROS (show ROS1 ELISA Kits) production promotes arterial EC specification in differentiating miPSCs by activating the Notch (show NOTCH1 ELISA Kits) signaling pathway and contributes to the angiogenic potency of transplanted miPSC-derived ECs.

Pig (Porcine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. These results suggested that resveratrol strongly enhances the RA-induced O2(-)-generating activity via up-regulation of gp91-phox gene expression in U937 cells.

  2. sub-vasomotor concentration of ET-1 (show EDN1 ELISA Kits) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 ELISA Kits) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 ELISA Kits) following ETA receptor activation

  3. Reactive oxygen species generated by NADPH oxidase (show NOX1 ELISA Kits) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

  4. Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.

CYBB Antigen Profile

Antigen Summary

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Gene names and symbols associated with CYBB

  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) antibody
  • cytochrome b-245, beta polypeptide (cybb) antibody
  • cytochrome b-245 heavy chain (CYBB) antibody
  • cytochrome b-245, beta polypeptide L homeolog (cybb.L) antibody
  • cytochrome b-245, beta polypeptide (CYBB) antibody
  • cytochrome b-245 beta polypeptide (CYBB) antibody
  • cytochrome b-245 beta chain (CYBB) antibody
  • cytochrome b-245, beta polypeptide (Cybb) antibody
  • cytochrome b-245 beta chain (Cybb) antibody
  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) antibody
  • NADPH oxidase heavy chain subunit (GP91-PHOX) antibody
  • AMCBX2 antibody
  • C88302 antibody
  • Cgd antibody
  • CGD91-phox antibody
  • CYBB antibody
  • Cyd antibody
  • GP91-1 antibody
  • Gp91-phox antibody
  • GP91PHOX antibody
  • NOX1 antibody
  • Nox2 antibody
  • p91-PHOX antibody
  • zgc:64144 antibody

Protein level used designations for CYBB

cytochrome b-245, beta polypeptide , gp91 , NADPH oxidase 2 , cytochrome b-245, beta polypeptide (chronic granulomatous disease) , Cytochrome b-245 heavy chain , NADPH oxidase heavy chain subunit , NADPH oxidase 1 , NADPH oxidase flavocytochrome b subunit , cytochrome b-245 heavy chain , gp91-phox , CGD91-phox , cytochrome b(558) subunit beta , cytochrome b558 subunit beta , heme-binding membrane glycoprotein gp91phox , neutrophil cytochrome b 91 kDa polypeptide , p22 phagocyte B-cytochrome , superoxide-generating NADPH oxidase heavy chain subunit , gp91-1 , endothelial type gp91-phox , predicted NADPH oxidase-2

GENE ID SPECIES
393386 Danio rerio
595081 Xenopus (Silurana) tropicalis
696542 Macaca mulatta
444353 Xenopus laevis
100036757 Ovis aries
100270807 Salmo salar
100008801 Oryctolagus cuniculus
1536 Homo sapiens
418581 Gallus gallus
281112 Bos taurus
13058 Mus musculus
66021 Rattus norvegicus
491825 Canis lupus familiaris
397108 Sus scrofa
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