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This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain..
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Human Polyclonal CYC1 Primary Antibody for ICC, IF - ABIN4301456
Maiti, Sharba, Navabi, Forsman, Fernandez, Lindén: IL-4 Protects the Mitochondria Against TNFα and IFNγ Induced Insult During Clearance of Infection with Citrobacter rodentium and Escherichia coli. in Scientific reports 2015
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Human Polyclonal CYC1 Primary Antibody for WB - ABIN1944852
Nishikimi, Ohta, Suzuki, Tanaka, Kikkawa, Tanaka, Kagawa, Ozawa: Nucleotide sequence of a cDNA encoding the precursor to human cytochrome c1. in Nucleic acids research 1988
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Human Polyclonal CYC1 Primary Antibody for WB - ABIN514809
Barjaktarovic, Schmaltz, Shyla, Azimzadeh, Schulz, Haagen, Dörr, Sarioglu, Schäfer, Atkinson, Zischka, Tapio: Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays. in PLoS ONE 2011
Cow (Bovine) Polyclonal CYC1 Primary Antibody for WB - ABIN2784726
Qattan, Radulovic, Crawford, Godovac-Zimmermann: Spatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cells. in Journal of proteome research 2012
these results indicate that CYC1 plays important roles in cell proliferation and comedo necrosis through the elevated oxidative phosphorylation activity in human ductal carcinoma in situ
results indicate that miR (show MLXIP Antibodies)-661 plays a tumor suppressor role in OS mediated by the downregulation of CYC1, suggesting a potential mechanism underlying cell death resistance in Osteosarcoma.
CYC1 promoted tumor metastasis via suppressing activation of AMPK (show PRKAA1 Antibodies) and contributed to tumor growth via facilitating production of ATP.
FASL (show FASL Antibodies), granzyme B, and cytochrome c (show CYCS Antibodies) blood expression reflects breast cancer progression and response to therapy. (Review)
our results provide evidence that CYC1 plays an important role in OS tumorigenesis, and modulation of CYC1 may be an effective strategy to potentiate OS to apoptotic induction by TRAIL.
Mutations in CYC1 cause insulin (show INS Antibodies)-responsive hyperglycemia.
HeLa cells expressing non-cleavable cytochrome c1 maintain mitochondrial morphology and functions.
Addition of H202 to tendon fibroblasts in vitro resulted in oxidative stress-induced (show SQSTM1 Antibodies) apoptosis and the release of CYC1.
the Ca(2 (show CA2 Antibodies)+) spike, mitochondrial Bcl-2 (show BCL2 Antibodies) presensitization, and subsequent Delta psi(m) transition, Bax (show BAX Antibodies) translocation, and ROS (show ROS1 Antibodies) generation are important upstream signals for cytochrome c (show CYCS Antibodies) release upon stimulation by a Bcl-2 (show BCL2 Antibodies) inhibitor.
Sensitivity of Cyt c (show CYCS Antibodies) detection in -linked immunosorbent assay is reduced in the presence of serum leucine-rich alpha-2-glycoprotein-1 (show LRG1 Antibodies).
Ngb (show NGB Antibodies) can bind to mitochondrial complex III subunit Cyc1, leading to suppression of oxygen-glucose deprivation -mediated complex III activity.
cytochrome c (show CYCS Antibodies) has a role in elimination of reactive oxygen species and hydrogen peroxide from mitochondria, and thus in apoptosis
An analysis of eight structures of mitochondrial bc(1) with bound quinol oxidation (Q(o)) site inhibitors revealed that the presence of inhibitors causes a bidirectional repositioning of the cd1 helix in the cytochrome b subunit.
This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.
, complex III subunit 4
, complex III subunit IV
, cytochrome b-c1 complex subunit 4
, cytochrome c1, heme protein, mitochondrial
, ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit