Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) ELISA Kits

CYP2C9 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C9 Antibodies (65) and CYP2C9 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP2C9 1559 P11712
CYP2C9    
CYP2C9    
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Top CYP2C9 ELISA Kits at antibodies-online.com

Showing 6 out of 26 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat 0.124 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$880.00
Details
Human < 0.236 ng/mL 0.625 ng/mL - 40 ng/mL   96 Tests Log in to see 11 to 18 Days
$867.02
Details
Rat < 0.124 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 11 to 18 Days
$938.09
Details
Eukaryotes
  100 Tests Log in to see 2 to 3 Days
$310.00
Details
Eukaryotes
  100 Tests Log in to see 2 to 3 Days
$385.00
Details

More ELISA Kits for CYP2C9 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) interaction partners

  1. Enzyme phenotyping with correlation analysis confirmed the predominant role of CYP2C9 in the biotransformation of siponimod and demonstrated the functional consequence of CYP2C9 genetic polymorphisms and fluconazole on siponimod metabolism.

  2. Comparisons of pharmacokinetics of 25 substrates CYP2C9, CYP2C19 (show CYP2C19 ELISA Kits), or CYP2D6 (show CYP2D6 ELISA Kits) in healthy Chinese and European subjects (classified with same enzyme activity) suggest that, for most substrates, limited interethnic pharmacokinetic differences exist (according to the databases used in this study). (CYP2C19 (show CYP2C19 ELISA Kits) = cytochrome P450 (show CYP ELISA Kits) family 2 subfamily C (show CYP ELISA Kits) member 19; CYP2D6 (show CYP2D6 ELISA Kits) = cytochrome P450 (show CYP ELISA Kits) family 2 subfamily D (show CYP ELISA Kits) member 6)

  3. genetic association studies in population in Scotland: data suggest, in type 2 diabetes treated with sulfonylureas, 2 SNPs in CYP2C9 (CYP2C9*2, R144C, rs1799853; CYP2C9*3, I359L, rs1057910) are associated with drug-induced hypoglycemia; an SNP in POR (POR (show POR ELISA Kits)*28, A503V, rs1057868) is associated with better response to sulfonylureas. (CYP2C9 = cytochrome P450 (show CYP ELISA Kits) family 2 subfamily C (show CYP ELISA Kits) member 9; POR (show POR ELISA Kits) = cytochrome p450 (show CYP ELISA Kits) oxidoreductase (show TXNRD1 ELISA Kits))

  4. The plasma S-warfarin (Cp(S)) time courses following the genotype-based dosing algorithms simulated using the PPK (show GJB2 ELISA Kits) estimates showed African Americans with CYP2C9*1/*1 and any of the VKORC1 (show VKORC1 ELISA Kits) genotypes would have an average Cp(S) at steady state 1.5-1.8 times higher than in Asians and whites.

  5. The final regression models for White and Black patients (Fig. 1) included age, weight, prosthetic valves, amiodarone use, CYP2C9*3, and VKORC1 (show VKORC1 ELISA Kits) 3673 G>A genotypes as covariates, whereas possession of CYP2C9*2 and simvastatin use were retained in the final model for White, but not Black patients.

  6. The present study confirms the variable distribution of CYP2C8 (*2 and *3) and CYP2C9 (*2 and *3) allelic polymorphisms among South Indian diabetic populations.

  7. Our results further support a minor contribution of CYP2C9 genetic variability toward steady-state endoxifen concentrations. Integration of clinician and genetic variables into individualized tamoxifen dosing algorithms would marginally improve their accuracy and potentially enhance tamoxifen treatment outcomes.

  8. CYP2C9 genetic variation was associated with long-term overall mortality and non-major bleeding in elderly patients treated with vitamin K antagonists.

  9. Until the age of 19, weight has a far greater effect on Vitamin K antagonist dosing variation than VKORC1 (show VKORC1 ELISA Kits) and CYP2C9 polymorphisms. During the age of 20-40years, VKORC1 (show VKORC1 ELISA Kits) and CYP2C9 polymorphisms play a significant role.

  10. CYP2C9*3 did show significant effect on warfarin dose requirement

CYP2C9 Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C9

  • cytochrome P450 family 2 subfamily C member 9 (CYP2C9) antibody
  • CPC9 antibody
  • CYP2C antibody
  • CYP2C10 antibody
  • CYPIIC9 antibody
  • P450IIC9 antibody

Protein level used designations for CYP2C9

cytochrome P-450 S-mephenytoin 4-hydroxylase , cytochrome P-450MP , cytochrome P450 2C9 , cytochrome P450 PB-1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
1559 Homo sapiens
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