Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteins

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes.

Data Quality
  • 6
Type
  • 15
    Protein
Antigen
  • 15
Reactivity
  • 12
  • 1
  • 1
  • 1
Application
  • 6
  • 6
  • 6
  • 2
  • 2
Host
  • 4
  • 2
  • 2
  • 2
  • 1
Binding Specificity
  • 3
  • 1
  • 1
  • 1
Conjugate
  • 7
  • 5
  • 1
  • 1
  • 1
Protein Type
  • 14
Format
  • 6
  • 3
  • 1
Biological Activity
  • 2
Suggested next Filters
15 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3078040
$9,371.15
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 60 Business Days
Recombinant Protein, Insect cells (Sf9) (Source), Purity > 40 %
ReactivityHuman
Application TCC, WB
Order details Cat. No. ABIN805485
$4,763.08
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1350974
$340.00
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN1099019
$688.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityHuman
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3009111
$689.42
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2712769
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2712768
$932.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
Recombinant Protein, Yeast (Pichia pastoris) (Source)
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2693650
$125.00
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Order details Cat. No. ABIN621791
ISO
$256.30
20 μg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application AcA, CC
Order details Cat. No. ABIN6238518
$774.00
50 μg
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source)
ReactivityRat (Rattus)
Application SDS, WB
Order details Cat. No. ABIN6378889
$1,744.65
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
ReactivityBonobo
Application ELISA
Order details Cat. No. ABIN1625688
$3,408.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
ReactivityChimpanzee
Application ELISA
Order details Cat. No. ABIN1625989
$3,408.17
1 mg
Plus shipping costs $45.00
Delivery in 60 to 71 Business Days
ReactivityHuman
Order details Cat. No. ABIN1062431
$5,397.86
Plus shipping costs $45.00
Will be delivered in 6 Business Days
Recombinant Protein, Insect cells (Sf9) (Source), Purity Glycosylated, so purity ≥40 % by SDS-PAGE
ReactivityHuman
Application SDS
Order details Cat. No. ABIN2506896
$6,300.00
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
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Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP2D6

  • cytochrome P450 family 2 subfamily D member 6 (CYP2D6) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) antibody
  • cytochrome 2D6 (CYP2D6) antibody
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) antibody
  • cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) antibody
  • cytochrome P450 family 2 subfamily D member 6 (cyp2d6) antibody
  • cytochrome P450 2D6 (CYP2D6) antibody
  • cytochrome P450 2D6-like (LOC100988273) antibody
  • CPD6 antibody
  • CYP2D antibody
  • cyp2d2 antibody
  • CYP2D6 antibody
  • cyp2d6-a antibody
  • CYP2D7AP antibody
  • CYP2D7BP antibody
  • CYP2D7P2 antibody
  • CYP2D8P2 antibody
  • CYP2D42 antibody
  • CYP2DL1 antibody
  • CYPIID6 antibody
  • MGC64445 antibody
  • P450-DB1 antibody
  • P450C2D antibody
  • P450DB1 antibody

Protein level used designations for CYP2D6

cytochrome P450 2D6 , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , debrisoquine 4-hydroxylase , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , cytochrome P450 2D6-like

GENE ID SPECIES
1565 Homo sapiens
470228 Pan troglodytes
678691 Macaca mulatta
100500743 Felis catus
379479 Xenopus laevis
446878 Xenopus laevis
548436 Xenopus (Silurana) tropicalis
100568286 Ovis aries
100988273 Pan paniscus
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