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CYP2J2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2J2 Kits (3) and CYP2J2 Proteins (3) and many more products for this protein.
Showing 10 out of 85 products:
Human Monoclonal CYP2J2 Primary Antibody for ELISA, WB - ABIN560550
Pearson, Warren, Barrett, Khan: Detection of EETs and HETE-generating cytochrome P-450 enzymes and the effects of their metabolites on myometrial and vascular function. in American journal of physiology. Endocrinology and metabolism 2009
Show all 4 Pubmed References
these data can aid the design of other analogues that have reduced cardiotoxicity, which do not modulate CYP2J2's arachidonic acid metabolism.
demonstrate that doxorubicin (DOX) and 7-de-aDOX inhibit CYP2J2-mediated AA metabolism and 7-de-aDOX binds close to the active site to alter the ratio of cardioprotective epoxyeicosatrienoic acids.
The use of LKY-047 as a selective CYP2J2 inhibitor.
Angiotensin II receptor blockers exhibit different degrees of inhibition of the metabolism of arachidonic acid by recombinant CYP2C9 (show CYP2C9 Antibodies), CYP2J2 and liver microsomes.
a computational investigation of the binding of arachidonic acid (AA) to CYP2J2 using homology modelling, induced fit docking (IFD) and molecular dynamics (MD) simulations.
Study found a significant interaction between CYP2J2- rs890293 and PPAR -gamma (show PPARG Antibodies)- rs1805192 and participants with GT or TT of rs890293 and CG or GG of rs1805192 genotype have the highest late-onset Alzheimer's disease risk, compared to participants with GG of rs890293 and CC of rs1805192 genotype.
dysregulation of the CYP (show PPIG Antibodies) epoxyeicosanoid pathway is a key pathological consequence of NASH (show SAMSN1 Antibodies)
CYP2J2 is widely expressed in tissues, especially heart, vascular smooth muscle, salivary glands and placenta. Recent studies have shown that overexpression of CYP2J2 in vivo reverses several pathological processes in animals, including hypertension and other cardiovascular pathologies and insulin (show INS Antibodies) resistance.
Homocysteine (Hcy) facilitated cytochrome P-450 (show CYP Antibodies) CYP2J2 (CYP2J2) upregulation in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cells by DNA demethylation.
Endothelial overexpression of CYP2J2 significantly changed oxylipin profiles.
CYP2J2 should be considered a prime candidate for understanding both genetic and physiological factors affecting serum 25OHD concentrations in cattle and, therefore, vitamin D status.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.
, arachidonic acid epoxygenase
, cytochrome P450 2J2
, cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, cytochrome P450, family 2, subfamily J, polypeptide 2
, LOW QUALITY PROTEIN: cytochrome P450 2J2