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CYP2S1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2S1 Proteins (3) and CYP2S1 Kits (2) and many more products for this protein.
Showing 10 out of 67 products:
Human Polyclonal CYP2S1 Primary Antibody for IF, IHC (p) - ABIN656566
Bui, Hankinson: Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli. in Molecular pharmacology 2009
Show all 3 Pubmed References
These results suggest that oxaliplatin exerts its inhibitory effects in human CRC cells via upregulation of CYP2S1 expression in a p53-dependent manner.
CYP2S1 regulates colorectal cancer growth through associated with prostaglandin E2-mediated activation of beta-catenin signaling.
The P450 2S1 may be involved in the reductive detoxication of several of the activated products of carcinogenic aromatic amines and heterocyclic aromatic amines.
found that CYP inhibition and siRNA-mediated downregulation of CYP2S1 increased macrophage phagocytosis
The reduction in CYP2S1 expression doubled intracellular PGE(2) levels.
Data suggest that CYP2S1 is induced in a keratinocyte cell line by exposure to all-trans retinoic acid and ultraviolet B radiation.
No association has been found between the CYP2J2 (rs890293, -76G > T) or CYP2S1 (rs34971233, 13106C > T, P466L and rs338583, 13255A > G) gene polymorphisms and respiratory diseases.
P450 2S1 can be reduced by NADPH-P450 reductase and suggest normal mixed-function oxidase roles of P450 2S1 to be revealed.
identify a novel regulatory cassette that mediates changes in Cyp2s1 expression
The presence of a CYP2A-related protein and testosterone metabolism in stellate cell cultures suggest that stellate cells express specific functional isoforms of CYP of which a major form is CYP2S1
identified the following three novel single nucleotide polymorphisms (SNPs): 4612G>A (Glu147Glu) in exon 3, 5478C>T (Leu230Leu) and 5479T>G (Leu230Arg, CYP2S1*5A) in exon 5 in Japanese individuals
12 genetic variations, which included the two novel nonsynonymous mutations CYP2S1 S61N (0.3%) and CYP2S1 L230R (0.8%), were identified in 50 Korean subjects
Review compares the expression of CYP2S1 mRNA and protein in humans, mice and rats, and critically examines evidence pertaining to CYP2S1 regulation and its catalytic activity.
CYP2S1 contributes to the metabolism of environmental carcinogens via a nicotinamide adenine dinucleotide phosphate (NADPH)- independent activity.
no Cyp2s1 protein was detected in aortae from wild-type mice it was expressed in aortae and macrophage foam cells from ApoE(-/-) mice
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens\; however, the specific function of the human protein has not been determined.
cytochrome P450 2S1
, cytochrome P450 family member predicted from ESTs
, cytochrome P540, subfamily IIS, polypeptide 1
, cytochrome P450, 2s1