anti-Cytochrome P450, Family 4, Subfamily Z, Polypeptide 1 (CYP4Z1) Antibodies

CYP4Z1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP4Z1 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP4Z1 199974 Q86W10
CYP4Z1    
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Top anti-CYP4Z1 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CYP4Z1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA Immunofluorescence analysis of HuvEc cells, using Cytochrome P450 4Z1 Antibody. The picture on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Cytochrome P450 4Z1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6274661 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6274661 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-CYP4Z1 Antibody in HL60 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$550.00
Details
Human Rabbit Un-conjugated ELISA, IF, IHC   100 μL Available
$359.79
Details
Human Mouse Un-conjugated WB Western Blot analysis of CYP4Z1 expression in transfected 293T cell line by CYP4Z1 MaxPab polyclonal antibody.Lane1:CYP4Z1 transfected lysate(55.55 KDa).Lane2:Non-transfected lysate. 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB HT29 lysates probed with CYP4Z1 Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C. 100 μL 3 to 7 Days
$327.80
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL 11 to 16 Days
$658.43
Details

More Antibodies against CYP4Z1 Interaction Partners

Human Cytochrome P450, Family 4, Subfamily Z, Polypeptide 1 (CYP4Z1) interaction partners

  1. We recently demonstrated the presence of the human CYP4Z1 on the plasma membrane of MCF-7 breast cancer cells and the detection of high titers of anti-CYP4Z1 aAbs in breast cancer patients, but not in healthy controls. In the present study we show that cells of the normal breast cell line MCF-10A do not display CYP4Z1 on their surface.

  2. If CYP4Z1 has a role to play in modulating cancer progression, new data form yeast microsomes expressing recombinant human enzyme suggest that the mechanism does not involve direct 20-HETE generation by this enzyme.

  3. This study reports on the creation of a new homology model of CYP4Z1 and performed molecular docking experiments, which indicate that all active substrates show a highly similar binding geometry compared to the endogenous substrates.

  4. CYP4Z1 3'UTR could inhibit the migration and Epithelial-mesenchymal transition of breast cancer cells.

  5. Data show that downregulation of cytochrome P450 family 4 CYP4Z1 or the pseudogene CYP4Z2P 3'-UTR promotes cell apoptosis.

  6. CYP4Z1 and CYP4Z2P were downregulated in MCF-7 cells compared with tamoxifen-resistant MCF-7-TamR cells

  7. Our findings suggest that the CYP4Z2P- and CYP4Z1-3'UTR promote breast cancer angiogenesis collectively by activating the PI3K and ERK1/2 pathways through binding multiple miRNAs.

  8. CYP4Z1 overexpression promotes tumor angiogenesis and growth in breast cancer partly via PI3K/Akt and ERK1/2 activation

  9. CYP4Z1, KIR and RDH10 could play a role in non-small-cell lung cancer progression

  10. Human cytochrome P450 (CYP), termed CYP4Z1,was identified, and the cDNA was cloned from a breast carcinoma line .

  11. PPARalpha has a role in CYP4X1 regulation, and the glucocorticoid and progesterone receptors have roles in CYP4Z1 gene activation

  12. CYP4Z1-dependent in-chain hydroxylation of lauric and myristic acid, which in both cases leads to the formation of four different monohydroxylated products at positions omega-2, omega-3, omega-4, and omega-5, respectively

CYP4Z1 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.

Gene names and symbols associated with CYP4Z1

  • cytochrome P450 family 4 subfamily Z member 1 (CYP4Z1) antibody
  • CYP4A20 antibody

Protein level used designations for CYP4Z1

CYPIVZ1 , cytochrome P450 4Z1

GENE ID SPECIES
199974 Homo sapiens
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