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High-affinity epithelial cell surface receptor for APF. Additionally we are shipping CKAP4 Antibodies (82) and CKAP4 Kits (1) and many more products for this protein.
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CKAP4 has a role as a Dickkopf1 (show DKK1 Proteins) receptor and in pancreatic and lung tumor progression
Human Prostate Basal cell hyperplasia is an expansion of p63 (show RPE65 Proteins).
APF binds specifically to sites within the cytoskeleton-associated protein 4 (CKAP4) extracellular domain
CLIMP-63 (also known as CKAP4), is the partner of triadin (show TRDN Proteins), is responsible for this association of triads and microtubules.
The still rudimentary information of how CLIMP-63 fulfills these different roles, what these are exactly and how post-translational modifications control them, will be discussed.
Although VIMP (show SELS Proteins) can interact with CLIMP-63 and Syn5L, it does not interact with MT-binding ER proteins (such as Reep1 (show REEP1 Proteins)) that shape the tubular smooth ER
revealed that CKAP4 could associate with EGFR (show EGFR Proteins) at basal status and the complex was reduced upon EGF (show EGF Proteins) stimulation, leading to release EGFR (show EGFR Proteins) into cytoplasm
Single nucleotide polymorphisms in p63 (show RPE65 Proteins) are implicated in the etiology of nonsyndromic bladder-exstrophy-epispadias complex.
Here we report that the combination of p63 (show RPE65 Proteins), a master regulator of epidermal development and differentiation, and KLF4 (show KLF4 Proteins), a regulator of epidermal differentiation, is sufficient to convert dermal fibroblasts to a keratinocyte phenotype.
CKAP4 was correlated with favorable clinical outcome and was an independent predictor for overall survival in hepatic cholangiocarcinoma patients.
p63 positively regulates desmosome adhesion by directly controlling the expression of several desmosome genes, including Dsp, Dsc3 (show DSC3 Proteins) and Dsg1 (show DSG1 Proteins).
Thus p63 closely interacts with SP-A (show SFTPA1 Proteins) and may play a role in the trafficking or the biological function of the surfactant protein.
High-affinity epithelial cell surface receptor for APF. Mediates the anchoring of the endoplasmic reticulum to microtubules.
cytoskeleton-associated protein 4
, 63 kDa membrane protein
, 63-kDa cytoskeleton-linking membrane protein
, transmembrane protein (63kD), endoplasmic reticulum/Golgi intermediate compartment
, type-II transmembrane protein p63
, late passage cDNA-1