DCP2 Decapping Enzyme Homolog (S. Cerevisiae) Proteins (DCP2)

The protein encoded by DCP2 is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). Additionally we are shipping DCP2 Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DCP2 70640 Q9CYC6
DCP2 167227 Q8IU60
Rat DCP2 DCP2 291604  
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Top DCP2 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 Days
$411.40
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Yeast Human His tag   100 μg Log in to see 8 to 11 Days
$484.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Yeast Orang-Utan His tag   1 mg Log in to see 60 to 71 Days
$3,059.83
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DCP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , ,
,

More Proteins for DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) Interaction Partners

Mouse (Murine) DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. ERK (show EPHB2 Proteins)-phosphorylated Dcp1a (show DCP1A Proteins) enhances its interaction with the decapping enzyme (show DCP1A Proteins) Dcp2 during early differentiation of 3T3-L1 cells.

  2. Recruitment of DCP1A (show DCP1A Proteins) and DCP2 increases the mRNA degradation capacity of the maturing oocyte so that by the 2-cell stage, most of the maternal mRNA is degraded.

  3. The results showed that DCP1A (show DCP1A Proteins) and DCP2 are critical in the transition from mRNA stability to instability during meiotic maturation and that mRNA degradation must be successful to execute the oocyte-to-zygote transition.

  4. In this study the increase in Irf-7 (show IRF7 Proteins) mRNA within the background of reduced Dcp2 levels was attributed to a stabilization of the Irf-7 (show IRF7 Proteins) mRNA, suggesting that Dcp2 normally modulates Irf-7 (show IRF7 Proteins) mRNA stability.

  5. Like Dcp2, Nudt16 (show NUDT16 Proteins) also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

Human DCP2 Decapping Enzyme Homolog (S. Cerevisiae) (DCP2) interaction partners

  1. Human Dcp2 levels and activity are controlled by a competition between decapping complex assembly and Dcp2 degradation.

  2. The data indicates that DCP2 activation by DCP1 (show ACE Proteins) occurs preferentially on the EDC4 (show EDC4 Proteins) scaffold, which may serve to couple DCP2 activation by DCP1 (show ACE Proteins) with 5'-to-3' mRNA degradation by XRN1 (show XRN1 Proteins) in human cells.

  3. Data show that Y14 (show RBM8A Proteins) interacts directly with the decapping factor Dcp2 and the 5' cap structure of mRNAs via different but overlapping domains.

  4. PNRC2 (show PNRC2 Proteins) acts in synergy with Dcp1a (show DCP1A Proteins) to stimulate the decapping activity of Dcp2 by bridging the interaction between Dcp1a (show DCP1A Proteins) and Dcp2.

  5. Like Dcp2, Nudt16 (show NUDT16 Proteins) also regulates the stability of a subset of mRNAs including a member of the motin family of proteins involved in angiogenesis.

  6. an mRNA decapping enzyme (show DCPS Proteins) demonstrated to contain intrinsic decapping activity

  7. Human Dcp2 is a catalytically active mRNA decapping enzyme (show DCPS Proteins) that localizes to the cytoplasm

  8. LSm1 (show LSM1 Proteins)-7 proteins colocalize with DCP1 (show ACE Proteins),DCP2 and Xrn1 (show XRN1 Proteins) in cytoplasmic foci

  9. These data support the novel notion of the association between Ro52 (show TRIM21 Proteins) with hDCP2 protein in cytoplasmic p-bodies, playing a role in mRNA metabolism in response to cellular stimulation.

DCP2 Protein Profile

Protein Summary

The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with DCP2

  • mRNA-decapping enzyme 2 (CpipJ_CPIJ019463)
  • mRNA-decapping enzyme 2 (PTRG_05936)
  • mRNA-decapping enzyme 2 (dcp2)
  • mRNA-decapping enzyme 2 (MCYG_05106)
  • mRNA-decapping enzyme 2 (MGYG_07617)
  • hypothetical protein (PGTG_03310)
  • mRNA-decapping enzyme 2 (Tsp_04018)
  • decapping mRNA 2 (dcp2)
  • decapping mRNA 2 (DCP2)
  • decapping mRNA 2 (Dcp2)
  • 2410015D23Rik protein
  • 5730537H01Rik protein
  • AL118268 protein
  • DDBDRAFT_0185453 protein
  • DDBDRAFT_0252811 protein
  • DDB_0185453 protein
  • DDB_0252811 protein
  • NUDT20 protein
  • RGD1562909 protein

Protein level used designations for DCP2

mRNA-decapping enzyme 2 , DCP2 decapping enzyme homolog , m7GpppN-mRNA hydrolase , hDpc , nudix (nucleoside diphosphate linked moiety X)-type motif 20

GENE ID SPECIES
6054129 Culex quinquefasciatus
6344191 Pyrenophora tritici-repentis Pt-1C-BFP
8624030 Dictyostelium discoideum AX4
9230993 Arthroderma otae CBS 113480
10025613 Arthroderma gypseum CBS 118893
10538062 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10904275 Trichinella spiralis
100195938 Salmo salar
489086 Canis lupus familiaris
70640 Mus musculus
100127054 Pongo abelii
167227 Homo sapiens
291604 Rattus norvegicus
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