anti-DDB1 and CUL4 Associated Factor 11 (DCAF11) Antibodies

DCAF11 encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Additionally we are shipping DCAF11 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCAF11 80344 Q8TEB1
DCAF11 28199 Q91VU6
DCAF11 305895 Q5M9G8
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Top anti-DCAF11 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-WDR23 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta Rabbit Anti-DCAF11 Antibody Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver Observed Staining: Cytoplasm in hepatocytes, strong signal, moderate tissue distribution Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Dcaf11 Antibody Titration: 1.0 ug/ml Positive Control: Mouse pancreas 100 μL Log in to see 2 to 3 Days
$319.00
Details
Guinea Pig Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DCAF11 Antibody [NBP1-83364] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & cytoplasm. Immunohistochemistry-Paraffin: DCAF11 Antibody [NBP1-83364] - Staining of human kidney shows moderate to strong positivity in tubular cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using DCAF11 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining of human kidney with WDR23 polyclonal antibody shows moderate to strong positivity in tubular cells at 1:20-1:50 dilution. Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with WDR23 polyclonal antibody at 1:250-1:500 dilution. 100 μL Log in to see 11 to 12 Days
$452.00
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details

More Antibodies against DCAF11 Interaction Partners

Human DDB1 and CUL4 Associated Factor 11 (DCAF11) interaction partners

  1. Here, the authors demonstrated that CUL4B forms an E3 ligase with RBX1 (RING-box 1), DDB1 (DNA damage binding protein 1), and DCAF11 (DDB1 and CUL4 associated factor 11) that promotes the ubiquitination of p21(Cip1) and regulates cell cycle progression in human osteosarcoma cells.

  2. CRL4(WDR23) is required for efficient histone mRNA 3' end processing to produce mature histone mRNAs for translation. CRL4(WDR23) binds and ubiquitylates SLBP in vitro and in vivo, and this modification activates SLBP function in histone mRNA 3' end processing without affecting its protein levels.

  3. CRL4-DCAF11 mediates the degradation of SLBP at the end of S phase and this degradation is essential for the viability of cells.

  4. ur results identify WDR23 as an alternative regulator of NRF2 proteostasis and uncover a cellular pathway that regulates NRF2 activity and capacity for cytoprotection independently of KEAP1.

  5. Includes the functional characterization of a similar protein in C. elegans and comparison to the human protein.

DCAF11 Antigen Profile

Protein Summary

This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with DCAF11

  • DDB1 and CUL4 associated factor 11 L homeolog (dcaf11.L) antibody
  • DDB1 and CUL4 associated factor 11 (dcaf11) antibody
  • DDB1 and CUL4 associated factor 11 (DCAF11) antibody
  • ddb1 and cul4 associated factor 11 (dcaf11) antibody
  • DDB1 and CUL4 associated factor 11 (Dcaf11) antibody
  • 0710008A13Rik antibody
  • C76035 antibody
  • D14Ucla1 antibody
  • Dacf11 antibody
  • DKFZP459A2062 antibody
  • GLO14 antibody
  • MGC53214 antibody
  • MGC88880 antibody
  • PRO2389 antibody
  • Wdr23 antibody
  • zgc:110066 antibody

Protein level used designations for DCAF11

DDB1 and CUL4 associated factor 11 , WD repeat domain 23 , DDB1- and CUL4-associated factor 11 , WD repeat-containing protein 23

GENE ID SPECIES
380436 Xenopus laevis
448206 Xenopus (Silurana) tropicalis
452808 Pan troglodytes
567578 Danio rerio
714867 Macaca mulatta
100173316 Pongo abelii
100189652 Pongo abelii
100606408 Nomascus leucogenys
80344 Homo sapiens
490621 Canis lupus familiaris
539433 Bos taurus
28199 Mus musculus
305895 Rattus norvegicus
Selected quality suppliers for anti-DCAF11 (DCAF11) Antibodies
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