DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) ELISA Kits

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. Additionally we are shipping DDX41 Antibodies (69) and DDX41 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DDX41 51428 Q9UJV9
DDX41 72935 Q91VN6
DDX41 314336  
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Top DDX41 ELISA Kits at antibodies-online.com

Showing 10 out of 10 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Rabbit 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Monkey 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Human 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Dog 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Mouse 0.1 ng/mL 2.5-50 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Sheep
  96 Tests 15 to 18 Days
$707.14
Details
Cow
  96 Tests 15 to 18 Days
$707.14
Details
Pig
  96 Tests 15 to 18 Days
$707.14
Details

More ELISA Kits for DDX41 Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. bi-allelic mutations in DDX41 could potentially be a new cancer predisposition syndrome associated with delayed psychomotor development

  2. Results show that the DDX41 DEAD domain recognizes both double-stranded DNA (dsDNA) and cyclic dinucleotides (CDN) at the same binding site. A structural comparison between the open and closed forms of the DDX41 DEAD domain revealed the structural rearrangement in the N-terminal region, which drastically changes the conformation of the ATP-binding site.

  3. analysis suggests that rather than establishing a causal Mendelian link between DDX41 germline LOF variants and MDS/AML it is appropriate to consider these as genetic risk factors

  4. Two novel germline DDX41 mutations in a family with inherited myelodysplasia/acute myeloid leukemia.

  5. Structural and functional analyses of human DDX41 DEAD domain.

  6. DDX41 mutations lead to development of high-risk myelodysplastic syndrome.(review)

  7. An increasing number of both inherited and acquired mutations in DDX41 gene are identified from myelodysplastic syndrome and/or acute myeloid leukemia (MDS/AML) patients.

  8. data demonstrate that DDX41 suppresses p21 translation without disturbing the function of p53 to directly induce p21 mRNA expression, this process indirectly requires p53, perhaps in the form of another p53 target gene or as a still undefined posttranscriptional function of p53.

  9. This study uncovered a pathogenic role of p.R525H DDX41 in the slow growth rate of tumor cells. Age-dependent epigenetic alterations or other somatic changes might collaborate with the mutation to cause AML.

  10. This study expands both the mutation and phenotypic spectra observed in families with germ line DDX41 mutations.

  11. corresponding deletions on 5q35.3 present in 6% of cases led to haploinsufficient DDX41 expression. DDX41 lesions caused altered pre-mRNA splicing and RNA processing

  12. results suggest a mechanism whereby c-di-GMP and c-di-AMP are detected by DDX41, which forms a complex with STING to signal to TBK1-IRF3 and activate the interferon response

  13. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

  14. The N-terminal domain of Abs interacts with the phox homology (PX) domain of SNX2 suggesting that PX domains may also participate in protein-protein interaction.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41) interaction partners

  1. Both DDX41 and cGAS are needed for the antiretroviral innate immune response to murine leukemia virus (MLV) and HIV in primary mouse macrophages and dendritic cells.

  2. Tyr364 and Tyr414 of DDX41 are critical for its recognition of AT-rich DNA and binding to STING, and tandem mass spectrometry identifies Tyr414 as the BTK phosphorylation site.

  3. TRIM21 is an interferon-inducible E3 ligase that induces the Lys48-linked ubiquitination and degradation of DDX41 and negatively regulates the innate immune response to intracellular double-stranded DNA.

  4. DDX41 is an additional DNA sensor that depends on STING to sense pathogenic DNA.

DDX41 Antigen Profile

Antigen Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Based on studies in Drosophila, the abstrakt gene is widely required during post-transcriptional gene expression.

Gene names and symbols associated with DDX41

  • DEAD-box helicase 41 (DDX41) antibody
  • probable ATP-dependent RNA helicase DDX41 (LOC100215941) antibody
  • DEAD-box helicase 41 (ddx41) antibody
  • probable ATP-dependent RNA helicase DDX41 (LOC100638079) antibody
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (Ddx41) antibody
  • DEAD-box helicase 41 (Ddx41) antibody
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 (ddx41) antibody
  • 2900024F02Rik antibody
  • AA958953 antibody
  • ABS antibody
  • AI324246 antibody
  • DDX41 antibody
  • wu:fb92e02 antibody
  • zgc:55896 antibody

Protein level used designations for DDX41

DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 , DEAD-box protein abstrakt , probable ATP-dependent RNA helicase DDX41-like , 2900024F02Rik , DEAD box protein 41 , DEAD box protein abstrakt homolog , probable ATP-dependent RNA helicase DDX41 , putative RNA helicase

GENE ID SPECIES
427630 Gallus gallus
462310 Pan troglodytes
700742 Macaca mulatta
100031917 Monodelphis domestica
100058316 Equus caballus
100215941 Hydra magnipapillata
100401323 Callithrix jacchus
100437507 Pongo abelii
100474236 Ailuropoda melanoleuca
100491281 Xenopus (Silurana) tropicalis
100550300 Meleagris gallopavo
100554935 Anolis carolinensis
100638079 Amphimedon queenslandica
51428 Homo sapiens
479274 Canis lupus familiaris
505276 Bos taurus
72935 Mus musculus
314336 Rattus norvegicus
394020 Danio rerio
101102307 Ovis aries
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