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DDX46 encodes a member of the DEAD box protein family.
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This study identified one of the Arabidopsis thaliana DEAD-box RNA helicases, AtRH7, as an interactor of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 (show HSPB3 Antibodies) (AtCSP3), which is an RNA chaperone involved in cold adaptation. [AtRH7]
Data indicate that human PROTEIN ISOASPARTYL METHYLTRANSFERASE (PIMT (show PCMT1 Antibodies)) can initiate isoAsp conversion to Asp (show ASIP Antibodies), and is able to restore Arabidopsis PRH75's complex biochemical activity provided isoAsp formation has not led to conformational alterations.
zebrafish Ddx46 is required for the multilineage differentiation of hematopoietic stem cells during development, through the regulation of specific gene expressions.
a model in which zebrafish Ddx46 is required for the development of the digestive organs and brain, possibly through the control of pre-mRNA splicing.
Knockdown of DDX46 inhibited osteosarcoma cell proliferation.
DDX46 is critical for ESCC cells proliferation.
DDX46 is critical for colorectal cancer (CRC (show CALR Antibodies)) cell proliferation and is a potential therapeutic target for CRC (show CALR Antibodies) treatment.
Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: DDX46.
characterization of protein associated with the human 17S U2 snRNP and one of its stable subunits, SF3b; results indicate that Prp5 plays an important role in pre-mRNA splicing, acting during or prior to prespliceosome assembly
Prp5 forms a bridge between U1 and U2 Small Nuclear Ribonucleoproteins at the time of pre-spliceosome formation
DDX46 inhibits antiviral innate responses by entrapping selected antiviral transcripts in the nucleus by erasing their m(6)A modification, a modification normally required for export from the nucleus and translation.
molecular cloning and immunohistochemical distribution and localization of RHL in non-diapause eggs
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex\; it plays an important role in pre-mRNA splicing.
DEAD box protein 46
, probable ATP-dependent RNA helicase DDX46
, PRP5 homolog
, Prp5-like DEAD-box protein
, RNA helicase
, DEAD box polypeptide 46
, helicase of 117.4 kDa