DEK Oncogene Proteins (DEK)

DEK encodes a protein with one SAP domain. Additionally we are shipping DEK Antibodies (63) and DEK Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DEK 7913 P35659
DEK 306817 Q6AXS3
DEK 110052 Q7TNV0
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Top DEK Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
Escherichia coli (E. coli) Cat Un-conjugated   5 applications Log in to see 1 to 2 Days

DEK Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Rat (Rattus)
Mouse (Murine)

More Proteins for DEK Oncogene (DEK) Interaction Partners

Human DEK Oncogene (DEK) interaction partners

  1. These findings define DEK as an important and multifunctional mediator of homologous recombination.

  2. DEK is detected in spontaneously forming neutrophil extracellular traps (NETs) from juvenile idiopathic arthritis patient synovial neutrophils, and DEK-targeted aptamers reduce NETs formation.

  3. High DEK proto-oncogene protein (DEK) expression associated with complete response to neoadjuvant chemoradiotherapy.

  4. High DEK expression is associated with cervical cancer tumorigenesis and metastasis.

  5. The results of the present study demonstrated that EMT of colorectal carcinoma cells was partially mediated by DEK, which likely affected the invasive ability of colorectal carcinoma cells. In addition, cell proliferation and apoptosis were susceptible to DEK silencing.

  6. RNA-sequencing proved to be a valuable tool for the detection of a fusion of genes DEK and NUP214 in a leukemia that showed cryptic cytogenetic rearrangement of chromosome band 9q34.

  7. DEK overexpression enhanced carcinogenesis, including field cancerization, in OSCC by stimulating the G1 /S phase transition and promoting DNA replication.

  8. DEK and LCMR1 were demonstrated to cooperate in the inhibition of apoptosis in lung cancer cells.

  9. High DEK expression is associated with breast cancer angiogenesis .

  10. our study indicates that DEK expression is required for tumorigenesis and metastasis of hepatocellular carcinoma

  11. High DEK expression is associated with melanoma progression.

  12. DEK correlates with IL6 expression in HPV16+/p16+ oropharyngeal squamous cell carcinomas (OPSCC).

  13. data support a scenario whereby overexpression of the human DEK oncogene reprograms keratinocyte metabolism to fulfill energy and macromolecule demands required to enable and sustain cancer cell growth

  14. Decreased DEK expression in plasma cells suggests a potential role of this gene in plasma cell development and lack of detectable DEK protein by IHC could be used as a biomarker for normal and malignant plasma cells

  15. Our data indicated DEK plays multiple roles to facilitate tumor growth and maintenance. It can be used as a potential target for astrocytic tumor diagnosis and gene therapy.

  16. High DEK expression is associated with pancreatic ductal adenocarcinoma.

  17. AP-2a is an important transcription factor of DEK expression, which is correlated with the methylation level of the DEK core promoter in hepatocellular carcinoma .

  18. miR-592 targets DEK transcript and suppresses hepatocellular carcinoma cell growth

  19. Results find that DEK binds to transcription start sites with a dual role in activation and repression of highly and ubiquitously expressed genes.

  20. The study identified the DEK oncoprotein as a critical factor that interacts with an essential upstream enhancer element of the EKLF promoter and exerts a positive effect on EKLF levels.

DEK Protein Profile

Protein Summary

This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DEK Oncogene Proteins (DEK)

  • DEK proto-oncogene (DEK)
  • DEK proto-oncogene (Dek)
  • DEK proto-oncogene L homeolog (dek.L)
  • DEK oncogene (DNA binding) (Dek)
  • DEK oncogene (LOC398543)
  • 1810019E15Rik protein
  • D6S231E protein
  • D13H6S231E protein
  • DEK protein

Protein level used designations for DEK Oncogene Proteins (DEK)

DEK oncogene (DNA binding) , protein DEK , DEK oncogene

7913 Homo sapiens
306817 Rattus norvegicus
462460 Pan troglodytes
540945 Bos taurus
610538 Canis lupus familiaris
100340537 Oryctolagus cuniculus
100380963 Xenopus laevis
110052 Mus musculus
420828 Gallus gallus
101090769 Felis catus
100731281 Cavia porcellus
100156871 Sus scrofa
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