anti-DIX Domain Containing 1 (DIXDC1) Antibodies

The protein encoded by DIXDC1 is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. Additionally we are shipping DIX Domain Containing 1 Proteins (8) and DIX Domain Containing 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DIXDC1 85458 Q155Q3
DIXDC1 330938 Q80Y83
DIXDC1 363062 Q2VUH7
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Top anti-DIX Domain Containing 1 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB Anti-DIXDC1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml. 50 μL 11 to 14 Days
$484.00
Details
Human Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Human Mouse Un-conjugated WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated IF, WB 100 μL 11 to 14 Days
$522.50
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg 6 to 8 Days
$445.50
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 13 to 16 Days
$396.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), IP Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml. 100 μL 11 to 14 Days
$595.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), IP, WB Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml. 100 μL 11 to 14 Days
$595.83
Details
Mouse Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$419.83
Details

Top referenced anti-DIX Domain Containing 1 Antibodies

  1. Zebrafish (Danio rerio) Polyclonal DIXDC1 Primary Antibody for ICC, IF - ABIN549059 : Soma, Shiomi, Keino-Masu, Masu: Expression of mouse Coiled-coil-DIX1 (Ccd1), a positive regulator of Wnt signaling, during embryonic development. in Gene expression patterns : GEP 2006 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal DIXDC1 Primary Antibody for ELISA, WB - ABIN4288484 : Wu, Jing, Ma, Wu, Ding, Fan, Fan: DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293 cells. in Cell biology international 2009 (PubMed)

More Antibodies against DIX Domain Containing 1 Interaction Partners

Human DIX Domain Containing 1 (DIXDC1) interaction partners

  1. High DIXDC1 expression is associated with Growth and Invasion of Gastric Cancer.

  2. these results demonstrate that DIXDC1 promotes the growth of acute myeloid leukemia cells, possibly through upregulating the Wnt/beta-catenin signaling pathway

  3. DIXDC1 silencing inhibited cell proliferation, invasion, and Wnt signaling in retinoblastoma cell lines. DIXDC1 was identified as a target gene of miR-186

  4. MiR-539 inhibits glioma cell proliferation and invasion by targeting DIXDC1.

  5. DIXDC1 might participate in the development of glioma.

  6. Overexpression of DIXDC1 correlates with enhanced cell growth and poor prognosis in human pancreatic ductal adenocarcinoma.

  7. found that DIXDC1 could promote cell proliferation via modulating cell cycle progression and PI3K/AKT signaling pathway in NHLs

  8. Taken together, our results suggest that DIXDC1 plays an important role in regulating prostate cancer cell proliferation and invasion. Targeting DIXDC1 by miR-1271 may be a promising therapeutic strategy for prostate cancer.

  9. Downregulated expression of DIXDC1 is associated with hepatocellular carcinoma.

  10. DIXDC1 was overexpressed in gastric cancer and correlated with poor prognosis.

  11. DIXDC1 is associated with stage and prognosis in non-small cell lung cancer, and may promote invasion and migration through PI3K-AKT/AP-1-dependent activation of metalloproteinases

  12. DIXDC1 depletion results in upregulation of Snail1 in a FAK-dependent manner, leading to increased cell invasion. MARK1 phosphorylation of DIXDC1 is required for its localization to focal adhesions and ability to suppress metastasis in mice.

  13. Transgenic DIXDC1 might contribute to pathophysiology underlying abnormal behaviors in schizophrenia and other major psychiatric disorders in mice.

  14. a molecular mechanism for Ccd1-mediated Wnt activation in that Ccd1 converts latent polymeric Dvl to a biologically active oligomer(s).

  15. This study reveal that Dixdc1 integrates DISC1 into Wnt-GSK3beta/beta-catenin-dependent and -independent signaling pathways during cortical development and further delineate how DISC1 contributes to neuropsychiatric disorders.

  16. Wnt/beta-catenin pathway activation might upregulate DIXDC1 through a post-translational mechanism by inhibiting the ubiquitin-mediated degradation of the DIXDC1 protein.

  17. KIAA1735 maps to human chromosome 11q23.1 and encodes a novel protein with a myosine-tail homologous domain and C-terminal DIX domain

  18. Ccd1 inhibits Axin-mediated JNK activation by simultaneously adopting two distinct mechanisms, one through conformational changes that disallow MEKK1 binding and the other via direct sequestration of MEKK4.

  19. Thus, our data provide the first evidence that l-DIXDC1 may act as a novel branching component in the Wnt signaling pathway targeting both beta-catenin-TCF complex for gene expression and cytoskeleton for regulating dynamics of actin filaments.

  20. DIXDC1 might play an important role during neurogenesis, overexpression of DIXDC1 in embryonic carcinoma P19 cells promoted neuronal differentiation, and inhibited gliogenesis induced by retinoic acid.

Mouse (Murine) DIX Domain Containing 1 (DIXDC1) interaction partners

  1. These findings suggest a novel regulatory mechanism by which mCcd1 modulates Wnt signaling through auto-inhibition of dynamic head-to-tail homopolymerization.

  2. DIXDC1 is a regulator of cortical dendrite and synaptic development.

  3. Abnormal behavior in Dixdc1 mice could elucidate molecular pathophysiology involving Disc1 in major mental illnesses.

  4. crystals of the Ccd1 DIX domain belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=72.9, b=75.7, c=125.6 A. An X-ray diffraction data set was collected at 3.0 A resolution

  5. a molecular mechanism for Ccd1-mediated Wnt activation in that Ccd1 converts latent polymeric Dvl to a biologically active oligomer(s).

  6. DIXDC1 encodes a novel protein with a myosine-tail homologous domain and C-terminal DIX domain

  7. mouse Ccd1 functions as a positive regulator of the Wnt/beta-catenin pathway. Furthermore, Ccd1 is highly expressed and co-localized with Wnt signaling molecules in the embryonic and adult brain.

Zebrafish DIX Domain Containing 1 (DIXDC1) interaction partners

  1. These results indicate that Ccd1 is a novel positive regulator in this Wnt signaling pathway during zebrafish neural patterning.

DIX Domain Containing 1 (DIXDC1) Antigen Profile

Protein Summary

The protein encoded by this gene is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. The encoded protein is found associated with gamma tubulin at the centrosome. Three transcript variants, two protein-coding and the other non-protein coding, have been found for this gene. The longer isoform also associates with actin stress fibers while the shorter isoform does not.

Gene names and symbols associated with DIXDC1

  • DIX domain containing 1 (DIXDC1) antibody
  • DIX domain containing 1 (dixdc1) antibody
  • DIX domain containing 1 (Dixdc1) antibody
  • DIX domain containing 1a (dixdc1a) antibody
  • DIX domain containing 1b (dixdc1b) antibody
  • 4930563F16Rik antibody
  • BC048182 antibody
  • ccd1 antibody
  • Ccd1Aalpha1L antibody
  • Ccd1Abeta1L antibody
  • Ccd1BalphaL antibody
  • Ccd1BbetaL antibody
  • Ccd1CL antibody
  • dixdc1 antibody
  • im:7138279 antibody
  • mKIAA1735 antibody

Protein level used designations for DIXDC1

DIX domain containing 1 , dixin-like , coiled-coil protein DIX1 , dixin , DIX domain-containing protein 1 , coiled-coil-DIX1 , DIX domain-containing protein 1-A , coiled-coil DIX 1 , coiled-coil protein DIX1-A , coiled-coil-DIX1-A , dixin-A

GENE ID SPECIES
419798 Gallus gallus
466779 Pan troglodytes
710847 Macaca mulatta
100032288 Monodelphis domestica
100061990 Equus caballus
100225366 Taeniopygia guttata
100349631 Oryctolagus cuniculus
100411324 Callithrix jacchus
100462633 Pongo abelii
100497786 Xenopus (Silurana) tropicalis
100548570 Meleagris gallopavo
100581393 Nomascus leucogenys
85458 Homo sapiens
608957 Canis lupus familiaris
541211 Bos taurus
330938 Mus musculus
363062 Rattus norvegicus
360137 Danio rerio
794716 Danio rerio
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