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Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.. Additionally we are shipping DDIT4L Proteins (8) and DDIT4L Kits (5) and many more products for this protein.
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Data showed that DDiT4L may be an important transducer of pathological stress to autophagy through mTOR (show FRAP1 Antibodies) signaling in the heart.
Axonal injury-induced upregulation of the stress-responsive REDD2 leads to mTOR (show FRAP1 Antibodies) inhibition triggering early dendritic arbor retraction, neuronal dysfunction and subsequent death of adult retinal neurons.
IRF-1 (show IRF1 Antibodies) physically interacts with REDD2 in the large cytoplasmic protein (show BLZF1 Antibodies) complex
SMHS1 was found to be expressed in skeletal muscle, and comparisons of its expression in atrophied versus hypertrophied muscles and in oxidative versus glycolytic muscles suggested that SMHS1 contributes to muscle energy metabolism phenotypes.
RTP801 (show DDIT4 Antibodies) and RTP801L work downstream of AKT (show AKT1 Antibodies) and upstream of TSC2 (show TSC2 Antibodies) to inhibit mTOR (show FRAP1 Antibodies) functions
REDD2 is enriched in skeletal muscle and inhibits mTOR (show FRAP1 Antibodies) signaling in response to leucine and stretch.
mediates monocyte cell death through a reduction in thioredoxin-1 (show TXNL1 Antibodies) expression
Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively.
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
DNA damage-inducible transcript 4-like protein
, DNA-damage-inducible transcript 4-like protein
, HIF-1 responsive protein RTP801-like
, skeletal muscle hindlimb suspension 1
, soleus muscle atrophied after hindlimb suspension protein 1
, homolog of mouse SMHS1
, protein regulated in development and DNA damage response 2
, regulated in development and DNA damage response 2
, DNA-damage-inducible transcript 4-like
, DNA-damage-inducible transcript 4-like protein-like
, Soleus muscle atrophied after hindlimb suspension protein 1