anti-Death Effector Domain Containing (DEDD) Antibodies

DEDD encodes a protein that contains a death effector domain (DED). Additionally we are shipping DEDD Proteins (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEDD 9191 O75618
DEDD 21945 Q9Z1L3
DEDD 83631 Q9Z2K0
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Top anti-DEDD Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using DEDD, antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with  (Red) at 1:2500. WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti DEDD1 Polyclonal Antibody, Unconjugated (ABIN872742) at 1:200 followed by conjugation to the secondary antibody and DAB staining Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated WB DEDD Antibody (Center)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the DEDD antibody detected the DEDD protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of DEDD using K562 whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: DEDD Antibody [NBP1-31686] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/Immunofluorescence: DEDD Antibody [NBP1-31686] - Paraformaldehyde-fixed HeLa, using DEDD antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with an alpha Tubulin antibody (Red) at 1:2500. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated WB Western blot analysis in MDA-MB453 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 11 to 13 Days
$335.04
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using DEDD antibody (ABIN5973422) at dilution of 1/100 (40x lens). Immunohistochemistry of paraffin-embedded human esophagus using DEDD antibody (ABIN5973422) at dilution of 1/100 (40x lens). 100 μL Log in to see 11 to 16 Days
$426.40
Details
Cow Rabbit Un-conjugated ICC, WB   100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: DEDD Antibody  - Immunohistochemical staining of human testis shows strong nuclear and cytoplasmic positivity in cells in seminiferous ducts and Leydig cells. 100 μL Log in to see 10 to 13 Days
$494.38
Details

More Antibodies against DEDD Interaction Partners

Human Death Effector Domain Containing (DEDD) interaction partners

  1. MicroRNA-17 inhibition overcomes chemoresistance and suppresses epithelial-mesenchymal transition through a DEDD-dependent mechanism in gastric cancer

  2. LINC00472 contributed to the increase in lung adenocarcinoma cell apoptosis and the inhibition of proliferation via regulating miR-24-3p/ DEDD.

  3. DEDD protein role in cell proliferation and migration of bladder cancer

  4. Via direct interaction with the class III PI-3-kinase (PI3KC3)/Beclin1, DEDD activated autophagy and induced the degradation of Snail and Twist, two master regulators of EMT

  5. FAS-associated death domain (FADD)-DED-induced reactive oxygen species (ROS) generation is triggered by membrane localization of FADD-DED, which shifts the cells into a state that stimulates and fuels ROS and ultimately results in cell death.

  6. DEDD forms nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC

  7. DEDD and DEDD2 may be important mediators for death receptors and that they may target caspases to the nucleus.

Mouse (Murine) Death Effector Domain Containing (DEDD) interaction partners

  1. In uteri of Dedd-/- mice, development of the decidual zone and the surrounding edema after embryonic implantation was defective. This was accompanied by disintegration of implantation site structure, leading to embryonic death before placentation.

  2. DEDD plays an important role in maintenance of the Akt protein level, which in consequence supports the efficient incorporation of glucose into skeletal muscles and adipose tissues.

  3. DEDD acts as a novel inhibitor of the mitotic Cdk1/cyclin B1 complex and is an impeder of cell mitosis, and its absence critically influences cell and body size via modulation of rRNA synthesis

  4. The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation.

  5. It regulates cell cycle and cell sizing. (review)

DEDD Antigen Profile

Protein Summary

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with DEDD

  • death effector domain containing (DEDD) antibody
  • death effector domain-containing (Dedd) antibody
  • CASP8IP1 antibody
  • DEDD1 antibody
  • Dedpro1 antibody
  • Deft antibody
  • FLDED1 antibody
  • KE05 antibody

Protein level used designations for DEDD

DEDPro1 , FLDED-1 , death effector domain-containing protein , death effector domain-containing testicular molecule , tumor necrosis factor (ligand) superfamily, member 19

GENE ID SPECIES
9191 Homo sapiens
21945 Mus musculus
83631 Rattus norvegicus
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