Death-Associated Protein Kinase 2 Proteins (DAPK2)

DAPK2 encodes a protein that belongs to the serine/threonine protein kinase family. Additionally we are shipping DAPK2 Antibodies (143) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DAPK2 23604 Q9UIK4
DAPK2 13143 Q8VDF3
Rat DAPK2 DAPK2 300799  
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Top DAPK2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 30 to 35 Days
$5,370.21
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Insect Cells Human GST tag   10 μg 3 to 4 Days
$310.00
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DAPK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Death-Associated Protein Kinase 2 (DAPK2) Interaction Partners

Human Death-Associated Protein Kinase 2 (DAPK2) interaction partners

  1. remission effect of DAPK2 on placental cell oxidative damage and apoptosis in HDCP via mTOR activation

  2. study reveals a unique calmodulin-independent mechanism for DAPK2 activation, critical to its function as a novel downstream effector of AMPK in autophagy

  3. This study suggests that miR-520g contributes to tumor progression and drug resistance by post-transcriptionally downregulating DAPK2 in patients with epithelial ovarian cancer

  4. Thyroid hormone promotes selective autophagy via induction of DAPK2-SQSTM1 cascade, which in turn protects hepatocytes from diethylnitrosamine-induced hepatotoxicity or carcinogenesis.

  5. miR-520h suppresses Death-associated protein kinase 2 (DAPK2) expression, as restoring DAPK2 abolished miR-520h-promoted drug resistance, and knockdown of DAPK2 mitigated cell death caused by the depletion of miR-520h.

  6. that Death-associated protein kinase 2 effector functions are influenced by the protein's subcellular localization

  7. This study links adipocyte expression of an autophagy-regulating kinase, lysosome-mediated clearance and fat cell lipid accumulation; it demonstrates obesity-related attenuated autophagy in adipocytes, and identifies DAPK2 dependence in this regulation.

  8. DAPK2 is a novel kinase of mTORC1 and is a potential new member of this multiprotein complex, modulating mTORC1 activity and autophagy levels under stress and steady-state conditions.

  9. DAPK2 regulates oxidative stress in cancer cells by preserving mitochondrial function

  10. DAPK2-induced apoptosis is negatively regulated by Akt and 14-3-3 proteins.

  11. DAPK2 is upregulated in uterosacral ligaments in pelvic organ prolapse

  12. The defect in chemotaxis in DAPK2-inactive granulocytes is likely a result of reduced polarization of the cells, mediated by a lack of MLC phosphorylation, resulting in radial F-actin and pseudopod formation.

  13. The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPalpha during granulocytic differentiation but repressed by PML-RARalpha in APL.

  14. DRP-1 and ZIPk most likely evolved from their ancient ancestor gene DAPk by two gene duplication events that occurred close to the emergence of vertebrates

  15. Sodium butyrate induced DAPK1/2 expression in human gastric cancer cells and this expression prompted apoptosis by decreasing FAK levels.

  16. High frequency of promoter hypermethylation of the death-associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients

  17. distinct methylation pattern in bladder cancer with frequent methylation of RARbeta, DAPK, E-cadherin, and p16.

  18. gene expression in colorectal and gastric cancer silenced by DNA methylation and histone deacetylation

  19. Results implicate a novel role for DAPK2 in the regulation of normal myelopoiesis.

  20. DAPK2 as a novel Sp1-dependent target gene for E2F1 and KLF6 in cell death response.

Mouse (Murine) Death-Associated Protein Kinase 2 (DAPK2) interaction partners

  1. Thyroid hormone promotes selective autophagy via induction of DAPK2-SQSTM1 cascade, which in turn protects hepatocytes from diethylnitrosamine-induced hepatotoxicity or carcinogenesis.

  2. This study links adipocyte expression of an autophagy-regulating kinase, lysosome-mediated clearance and fat cell lipid accumulation; it demonstrates obesity-related attenuated autophagy in adipocytes, and identifies DAPK2 dependence in this regulation.

  3. DAPK2 is strongly and specifically expressed in interstitial cells of the cortex, providing a useful marker for this important cell population

  4. The defect in chemotaxis in DAPK2-inactive granulocytes is likely a result of reduced polarization of the cells, mediated by a lack of MLC phosphorylation, resulting in radial F-actin and pseudopod formation.

  5. These results suggest that DAPK2 is one of the targets of cGK-I in apoptosis induction.

  6. The crystal and solution structures of murine DAPK2 were determined in the presence of the autoinhibitory domain, with and without bound nucleotides in the active site. Dimers of DAPK2 had a conformation that did not permit protein substrate binding.

  7. DAPK2 was substantially up-modulated during late erythropoiesis

DAPK2 Protein Profile

Protein Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.

Gene names and symbols associated with DAPK2

  • death-associated protein kinase 2 L homeolog (dapk2.L)
  • death associated protein kinase 2 (DAPK2)
  • death-associated protein kinase 2b (dapk2b)
  • death-associated protein kinase 2 (dapk2)
  • death-associated protein kinase 2 (Dapk2)
  • dapk2 protein
  • DRP-1 protein
  • DRP1 protein

Protein level used designations for DAPK2

death-associated protein kinase 2 , DAP kinase 2 , DAP-kinase-related protein 1 beta isoform , DRP-1 , death-associated kinase 2

GENE ID SPECIES
496293 Xenopus laevis
529131 Bos taurus
556756 Danio rerio
706421 Macaca mulatta
747631 Pan troglodytes
100066921 Equus caballus
100145135 Xenopus (Silurana) tropicalis
23604 Homo sapiens
13143 Mus musculus
300799 Rattus norvegicus
610682 Canis lupus familiaris
100155578 Sus scrofa
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