anti-Debranching Enzyme Homolog 1 (S. Cerevisiae) (DBR1) Antibodies

The protein encoded by DBR1 is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. Additionally we are shipping DBR1 Proteins (16) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DBR1 51163 Q9UK59
DBR1 83703 Q923B1
DBR1 681234  
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Top anti-DBR1 Antibodies at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of HepG2 cells, using DBR1 antibody. ABIN6273108 at 1/100 staining Human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated IF, ELISA, WB Western Blot analysis of DBR1 expression in transfected 293T cell line by DBR1 monoclonal antibody (M01), clone 3A7.Lane 1: DBR1 transfected lysate(61.6 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged DBR1 is 0.03 ng/ml as a capture antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Porcine Cerebrum lysate; Primary Ab: 3µg/ml Rabbit Anti-Human DBR1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 15 to 18 Days
$350.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of DBR1 expression in transfected 293T cell line by DBR1 MaxPab polyclonal antibody.Lane 1: DBR1 transfected lysate(59.84 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to DBR1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$390.50
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$390.50
Details
Human Rabbit Biotin WB   100 μL 11 to 14 Days
$405.17
Details
Human Rabbit FITC WB   100 μL 11 to 14 Days
$419.83
Details
Human Rabbit Biotin WB   100 μL 11 to 14 Days
$405.17
Details

More Antibodies against DBR1 Interaction Partners

Human Debranching Enzyme Homolog 1 (S. Cerevisiae) (DBR1) interaction partners

  1. findings support a new view of the early steps in HIV genome replication - they support a model in which lariat formation of viral genomic RNA is important for minus-strand transfer, with DBR1 being required to resolve the lariat to allow reverse transcription to proceed

  2. Transcriptomic sequencing confirmed the effect of hDBR1 on RNA splicing, and metabolite profiling supported the observation that neoplasm is triggered by a decrease in hDBR1 expression both in vitro and in vivo.

  3. saturation mutagenesis of DBR1 and Gal4 and show that the experimental phenotypes for over 80% of the mutations correlate well with predicted effects of mutations on protein stability and RNA binding affinity.

  4. Results of protein-protein interaction between human Dbr1 and factors found in the Intron Large complex identify Xab2 and a novel protein CWF19L1 as specific interactors of DBR1.

  5. Inhibition of DBR1 caused a significant reduction in the formation of intermediate and full-length HIV-1 cDNA.

  6. Dbr1 protein cleaves the 2'-5' phosphodiester bond of intron lariats, necessary for subsequent intron degradation that follows pre-mRNA splicing.

Arabidopsis thaliana Debranching Enzyme Homolog 1 (S. Cerevisiae) (DBR1) interaction partners

  1. Lariat RNAs localized in nuclear bodies, and partially co-localize with HYL1, and both DCL1 and HYL1 were mis-localized in dbr1-2... we thus propose that lariat RNAs, as decoys, inhibit miRNA processing, suggesting a hitherto unknown layer of regulation in miRNA biogenesis.

DBR1 Antigen Profile

Protein Summary

The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication.

Gene names and symbols associated with DBR1

  • debranching RNA lariats 1 (DBR1) antibody
  • debranching RNA lariats 1 (Dbr1) antibody
  • debranching RNA lariats 1 (dbr1) antibody
  • debranching enzyme homolog 1 (S. cerevisiae) (dbr1) antibody
  • Lariat debranching enzyme (dbr-1) antibody
  • debranching enzyme 1 (DBR1) antibody
  • RNA lariat debranching enzyme Dbr1 (dbr1) antibody
  • debranching RNA lariats 1 S homeolog (dbr1.S) antibody
  • ARABIDOPSIS THALIANA DEBRANCHING ENZYME 1 antibody
  • ATDBR1 antibody
  • AW018415 antibody
  • dbr1 antibody
  • dbr1-a antibody
  • dbr1-b antibody
  • debranching enzyme 1 antibody
  • F28M20.40 antibody
  • F28M20_40 antibody
  • wu:fc08f08 antibody
  • zgc:63930 antibody

Protein level used designations for DBR1

RNA lariat debranching enzyme , debranching enzyme homolog 1 , lariat debranching enzyme , debranching enzyme homolog 1 (S. cerevisiae) , lariat debranching enzyme-like , lariat debranching enzyme B

GENE ID SPECIES
51163 Homo sapiens
83703 Mus musculus
323746 Danio rerio
429118 Gallus gallus
470936 Pan troglodytes
530188 Bos taurus
609194 Canis lupus familiaris
681234 Rattus norvegicus
716467 Macaca mulatta
100024249 Monodelphis domestica
100053540 Equus caballus
100380547 Salmo salar
100393126 Callithrix jacchus
100462550 Pongo abelii
100580054 Nomascus leucogenys
172357 Caenorhabditis elegans
829305 Arabidopsis thaliana
2542277 Schizosaccharomyces pombe 972h-
380060 Xenopus laevis
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