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DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. Additionally we are shipping DAD1 Kits (8) and DAD1 Proteins (5) and many more products for this protein.
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Human Polyclonal DAD1 Primary Antibody for ICC, ELISA - ABIN1002188
Nakashima, Sekiguchi, Kuraoka, Fukushima, Shibata, Komiyama, Nishimoto: Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. in Molecular and cellular biology 1993
Show all 4 Pubmed References
this study shows that abnormal expression of DAD1 may relate to the hyperfunction of immune responses and excessive apoptosis of severe aplastic anemia CD34 (show CD34 Antibodies)(+) cells
single-nucleotide polymorphisms in DAD1 gene is associated with neuroendocrine tumor.
DAD1 gene expression is decreased in follicular variant of papillary thyroid carcinoma.
DAD1 protein overexpression is associated with small bowel carcinoid tumors
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
, oligosaccharyl transferase subunit DAD1
, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
, defender against cell death 1
, oligosaccharyltransferase 2 homolog
, oligosaccharyltransferase subunit 2 (non-catalytic)
, defender against death (DAD1)
, apoptotic suppressor
, defender against cell death 1 protein
, defender against death protein 1
, defender against apoptotic cell death
, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad1
, oligosaccharyl transferase subunit dad1
, Oligosaccharyl transferase subunit DAD1
, false DAD1