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Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Additionally we are shipping Defensin, alpha 1B Antibodies (3) and and many more products for this protein.
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Human Neutrophil Peptide 1 directly binds and neutralizes Exotoxin A of Pseudomonas aeruginosa.
Inflammatory regulation of defensin alpha 1 (human neutrophil peptide 1; HNP-1) in pancreatic ductal adenocarcinoma (PDAC) tissue and cells indicates that HNP-1 may be a link between chronic inflammation and malignant transformation in the pancreas.
binding of HNP1 to affected bacterial toxins caused their local unfolding, potentiated their thermal melting and precipitation, exposed new regions for proteolysis, and increased susceptibility to collisional quenchers.
DEFA1B encodes an antibacterial peptide that is bacteriocidal against S. aureus, E. coli, and P. aeruginosa.
Data show that H. pylori induces alpha-defensin release from granulocytes, which may be important in local host response to H. pylori infection in gastroduodenal diseases.
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
neutrophil defensin 1