Defensin, alpha 5, Paneth Cell-Specific (DEFA5) ELISA Kits

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. Additionally we are shipping Defensin, alpha 5, Paneth Cell-Specific Antibodies (54) and Defensin, alpha 5, Paneth Cell-Specific Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DEFA5 1670 Q01523
DEFA5 13239  
DEFA5 286995 Q62715
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Top Defensin, alpha 5, Paneth Cell-Specific ELISA Kits at

Showing 10 out of 36 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 5.9 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
Mouse 13.1 pg/mL 31.2 pg/mL - 2000 pg/mL 96 Tests 13 to 16 Days
Rat 37.5 pg/mL 62.5-4000 pg/mL Typical standard curve 96 Tests 12 to 14 Days
Rabbit 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days
Guinea Pig 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days
Pig 9.375 pg/mL 15.625-1000 pg/mL   96 Tests 12 to 14 Days
Chicken 0.469 pg/mL 0.781-50 pg/mL   96 Tests 12 to 14 Days
Sheep 0.1 ng/mL 5-100 ng/mL   96 Tests 15 to 18 Days
Monkey 1.0 pg/mL 25-500 pg/mL   96 Tests 15 to 18 Days
Dog 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days

Top referenced Defensin, alpha 5, Paneth Cell-Specific ELISA Kits

  1. Human DEFA5 ELISA Kit for Sandwich ELISA - ABIN415097 : Alam, Rashid, Kabir, Raqib, Ahmad: On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment. in Vaccine 2014 (PubMed)

More ELISA Kits for Defensin, alpha 5, Paneth Cell-Specific Interaction Partners

Human Defensin, alpha 5, Paneth Cell-Specific (DEFA5) interaction partners

  1. DEFA5 rs4415345 and rs4610776 were associated with altered incidence of aGVHD grade II-IV

  2. this study demonstrates that age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

  3. In contrast to oxidized peptides, some reduced defensins exhibit increased vulnerability to proteolytic degradation. In this report, we investigated the susceptibility of Paneth-cell-specific human alpha-defensin 5 (HD-5) and -6 (HD-6) to intestinal proteases using natural human duodenal fluid

  4. Plasma alpha-Defs 1-3 concentrations correlate with the degree of inflammation and appear to be specific biomarkers of ileal-Crohn's disease at diagnosis. Ileal alpha-Def 5 expression is down-regulated permanently by methylation.

  5. The binding mechanisms of HD5 on lipopolysaccharide in comparison to a bare DMPC lipid membrane was studied using molecular dynamics (MD) simulations.

  6. Bifidobacterium infantis NLS super strain decreases Paneth cell counts and expression of alpha-defensin-5 in celiac disease.

  7. Human alpha-Defensin-5 is a potential candidate biomarker to molecularly differentiate Crohn's colitis from ulcerative colitis, to our knowledge. These data give us both a potential diagnostic marker in Human alpha-Defensin-5 and insight to develop future mechanistic studies to better understand crypt biology in Crohn's colitis.

  8. Different dynamics and pathway of disulfide bonds reduction has been demonstrated for two human defensins, HD5 and HBD-3.

  9. These data support capsid stabilization and redirection to the lysosome during infection as a general antiviral mechanism of alpha-defensins against nonenveloped viruses.

  10. Human adenovirus 3 produces large amounts of penton-dodecahedra (PtDd), virus-like particles, during replication, which also function in blocking of HD5.

  11. no biologic differences between wild-type HD5 and its variants were observed on HD5 antibacterial activity against Escherichia coli

  12. a moderately active linear peptide derived from the alpha-defensin HD5 can be engineered to enhance antimicrobial activity almost comparable to the native peptide.

  13. The study used ion mobility coupled to mass spectrometry to track the structural changes in HD-5 upon disulfide bond reduction.

  14. The study reports the screening of human defensin 5 against the Keio Collection of E. coli strains and shows how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.

  15. Authors show that although NOD2 by itself can slightly up-regulate expression of HD5 and HD6, it can strongly down-regulates their expression during differentiation of the Paneth cell lineage mainly by inhibiting activation of the MAPK pathway.

  16. HD5ox, at least in part, exerts its antibacterial activity against E. coli and other Gram-negative microbes in the cytoplasm.

  17. These data support a model in which HD5 prevents furin from accessing human papillomavirus 16 L2 by occluding the furin cleavage site via direct binding to the viral capsid.

  18. Enteric alpha-defensin HD5 and beta-defensin hBD2 shared similar toxin-unfolding effects with HNP1, albeit to different degrees.

  19. our results highlight the potential contribution of altered alpha-defensin HD-5 expression in the formation of a viral/tumour-permissive environment in high-risk HPV infection and progression to cancer of the uterine cervix

  20. DEFA5 displays antimicrobial activity against E. coli, E. aerogenes, B. cereus, and S. aureus.

Mouse (Murine) Defensin, alpha 5, Paneth Cell-Specific (DEFA5) interaction partners

  1. alpha-defensin 5 expression can also be regulated by microbial metabolites

  2. Data show that DEFA5-expressing mice had striking losses of segmented filamentous bacteria and fewer interleukin 17 (IL-17)-producing lamina propria T cells.

Defensin, alpha 5, Paneth Cell-Specific (DEFA5) Antigen Profile

Antigen Summary

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Gene names and symbols associated with DEFA5

  • defensin alpha 5 (DEFA5) antibody
  • defensin, alpha, 5 (Defa5) antibody
  • defensin, alpha 5, Paneth cell-specific (DEFA5) antibody
  • defensin alpha 5 (Defa5) antibody
  • alpha-defensin 1A (MNP1A) antibody
  • DEF5 antibody
  • Defa antibody
  • DEFA1 antibody
  • DEFA5 antibody
  • Defa29 antibody
  • Defcr5 antibody
  • Defcr29 antibody
  • HD-5 antibody

Protein level used designations for DEFA5

HD5(20-94) , defensin 5 , defensin, alpha 5, preproprotein , defensin-5 , alpha-defensin 5 , defensin, alpha, 29 , defensin-related cryptdin-5 , alpha-defensin 5, Paneth cell-specific , defensin, alpha 1 , Paneth cell-specific alpha-defensin 5 , defensin NP-2 , neutrophil antibiotic peptide NP-1 , neutrophil antibiotic peptide NP-2 , neutrophil defensin 1 , neutrophil defensin 2 , ratNP-1 , ratNP-2 , Neutrophil defensin 1 , Neutrophil defensin 3 , RMAD-1 , RMAD-3 , RMAD-8 , neutrophil defensin 8

1670 Homo sapiens
13239 Mus musculus
463972 Pan troglodytes
100307028 Equus caballus
286995 Rattus norvegicus
574196 Macaca mulatta
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