DEFA5 Products
(Defensin, alpha 5, Paneth Cell-Specific (DEFA5))
Categories
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Jul 2008].
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Featured DEFA5 Categories
DEFA5 Antibodies
High quality antibodies with extensive validation data.
DEFA5 ELISA Kits
Reliable ELISA kits for a wide range of species.
DEFA5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DEFA5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7190461
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN514948
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), IF
Validations
- (2)
- (1)
Cat. No.
ABIN534052
Quantity
100 μL
Datasheet
Datasheet
Recommended DEFA5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955307
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999455
Quantity
96 tests
Datasheet
Datasheet
Recommended DEFA5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1351413
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412587
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7412590
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our DEFA5 products
: "Alarin in different human intestinal epithelial cell types." in: Histochemistry and cell biology, (2019) (PubMed).: "Alpha-defensins (α-Defs) in Crohn's disease: decrease of ileal α-Def 5 via permanent methylation and increase in plasma α-Def 1-3 concentrations offering biomarker utility." in: Clinical and experimental immunology, (2018) (PubMed).
: "LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients." in: JCI insight, Vol. 2, Issue 6, pp. e91917, (2017) (PubMed).
: "Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling." in: Cell stem cell, Vol. 21, Issue 1, pp. 51-64.e6, (2017) (PubMed).
: "Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy." in: Journal of virology, Vol. 91, Issue 6, (2017) (PubMed).
: "Paneth cell defects in Crohn's disease patients promote dysbiosis." in: JCI insight, Vol. 1, Issue 8, pp. e86907, (2016) (PubMed).
: "On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment." in: Vaccine, Vol. 33, Issue 1, pp. 18-21, (2014) (PubMed).
: "Lowered expression of galectin-2 is associated with lymph node metastasis in gastric cancer." in: Journal of gastroenterology, Vol. 47, Issue 1, pp. 37-48, (2012) (PubMed).
: "Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes." in: Journal of proteomics, Vol. 75, Issue 10, pp. 2983-97, (2012) (PubMed).
: "[Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling]." in: Molekuliarnaia biologiia, Vol. 45, Issue 2, pp. 376-81, (2011) (PubMed).
Synonyms and alternative names related to DEFA5
defensin alpha 5 (DEFA5), defensin, alpha, 5 (Defa5), defensin, alpha 5, Paneth cell-specific (DEFA5), defensin alpha 5 (Defa5), alpha-defensin 1A (MNP1A), DEF5, Defa, DEFA1, DEFA5, Defa29, Defcr5, Defcr29, HD-5Protein level used designations for DEFA5
- HD5(20-94)
- defensin 5
- defensin, alpha 5, preproprotein
- defensin-5
- alpha-defensin 5
- defensin, alpha, 29
- defensin-related cryptdin-5
- alpha-defensin 5, Paneth cell-specific
- defensin, alpha 1
- Paneth cell-specific alpha-defensin 5
- defensin NP-2
- neutrophil antibiotic peptide NP-1
- neutrophil antibiotic peptide NP-2
- neutrophil defensin 1
- neutrophil defensin 2
- ratNP-1
- ratNP-2
- Neutrophil defensin 1
- Neutrophil defensin 3
- RMAD-1
- RMAD-3
- RMAD-8
- neutrophil defensin 8
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