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Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping beta Defensin 1 Kits (47) and beta Defensin 1 Proteins (46) and many more products for this protein.
Showing 10 out of 162 products:
Human Polyclonal beta Defensin 1 Primary Antibody for IHC (p), ELISA - ABIN2473295
Goldman, Anderson, Stolzenberg, Kari, Zasloff, Wilson: Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. in Cell 1997
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Human Polyclonal beta Defensin 1 Primary Antibody for ELISA, WB - ABIN2473296
Kelly, Glover, Campbell, Kominsky, Ehrentraut, Bowers, Bayless, Saeedi, Colgan: Fundamental role for HIF-1? in constitutive expression of human ? defensin-1. in Mucosal immunology 2013
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hBD-1 potentiates the induction of in vitro osteoclastogenesis by RANKL via enhanced phosphorylation of the p44/42 MAPKs.
findings lead us to hypothesize an involvement of hBD-1 mediated innate immunity in the modulation of the susceptibility towards adeno (show ADORA2A Antibodies)-tonsillar hypertrophy development.
Two DEFB1 SNPs were significantly associated with the DMFT(decayed, missing, filled teeth) index.
Multivariate logistic regression analysis showed that hBD-1 basal cell loss (>/=20% of prostatic glands in total cores) is an independent factor for predicting prostatic adenocarcinoma (odds ratio: 4.739, confidence interval: 1.093-20.554, p = 0.038). hBD-1 loss of basal cells is a useful indicator to identify extremely high-risk patients with initially negative biopsy.
It was concluded that bile acids can differentially regulate colonic epithelial beta-defensin expression and secretion; the authors discuss the implications for intestinal health and disease.-
data provide important insight into the in vivo kinetics of HBD (show HBd Antibodies) expression, the mechanism of HBD1 induction by HIV-1, and the role of HBDs in the early innate response to HIV-1 during acute infection
CpG methylation frequencies in the DEFB1 low CpG-content promoter were significantly higher in the prostate malignant tissues than in adjacent benign tissues.
DEFB1 - genotypes were correlated with the hBD-1 salivary concentration.
Coding missense and nonsense single nucleotide polymorphisms result in less active HBD1 antibacterial activity against Escherichia coli.
A significant difference was found between the levels of staining of TLR-2, TLR-4 (show TLR4 Antibodies) and hBD-1 in different lesions from the epidermis, inflammation region, dermis and skin appendages (p < 0.05) in patients with acne vulgaris.
Fenofibrate and gemfibrozil inhibit LPS (show TLR4 Antibodies)-induced inflammatory activation of macrophages via PPARalpha (show PPARA Antibodies)/beta-defensin 1/TLR4 (show TLR4 Antibodies) pathway.
these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis
Akt1 (show AKT1 Antibodies) is involved in the regulation of defensin (show DEF Antibodies) expression and the innate immune response important for bacterial clearance
Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice
The decreased production of antimicrobial peptides by burn-site epidermal keratinocytes influenced by Gr-1 (show GSR Antibodies)(+)CD11b (show ITGAM Antibodies)(+) cells was shown to be restored by glycyrrhizin.
elimination of mBD-1 results in a defect in the ability of the host to clear H. influenzae from the lung, which is most consistent with this peptide functioning as an antibiotic at the airway surface.
The expression of BD1 was significantly elevated in the lungs of cigarette smoke-exposed mice compared with air-exposed mice.
Although both murine beta-defensin (mBD)-1 and mBD2 (show MBD2 Antibodies) are constitutively expressed in normal BALB/c and C57BL/6 corneas, mBD-1 is not required for host resistance against Pseudomonas aeruginosa-induced corneal infection.
pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide.
Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line.
Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
, beta-defensin 1
, Gal 1
, Gal 1-alpha
, antimicrobial peptide 1
, antimicrobial peptide CHP2
, chicken heterophil peptide 2
, gal-1 alpha
, gallinacin-1 alpha
, beta defensin-1 homolog
, prepro-beta-defensin 1
, Beta-defensin 1
, Defensin, beta 1
, DEFB1-like protein
, beta defensin 1