anti-Dentin Sialophosphoprotein (DSPP) Antibodies

DSPP encodes two principal proteins of the dentin extracellular matrix of the tooth. Additionally we are shipping Dentin Sialophosphoprotein Kits (27) and Dentin Sialophosphoprotein Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DSPP 1834 Q9NZW4
DSPP 25254  
DSPP 666279  
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Top anti-Dentin Sialophosphoprotein Antibodies at

Showing 9 out of 12 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p) Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Rabbit Anti-DSPP Polyclonal Antibody, Unconjugated (ABIN2559412) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of MCF7 and HL60 cells, using DSPP antibody. 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated WB DSPP Antibody (N-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DSPP antibody detected the DSPP protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
Mouse Rabbit Un-conjugated WB Western Blot: DSPP Antibody [NBP1-91612] - SP2/0 cell lysate, concentration 0.125ug/ml. 100 μL Log in to see 8 to 11 Days
Human Rabbit Biotin IHC (p)   100 μL Log in to see 14 to 21 Days
Mouse Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated   400 μL Log in to see 11 to 16 Days
Human Rabbit Un-conjugated   1 mg Log in to see 16 to 26 Days

DSPP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,

Rat (Rattus)

Mouse (Murine)

Top referenced anti-Dentin Sialophosphoprotein Antibodies

  1. Human Polyclonal DSPP Primary Antibody for IHC (p) - ABIN2559412 : Zhan, Liu, Wang: The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway. in Journal of cellular biochemistry 2017 (PubMed)

More Antibodies against Dentin Sialophosphoprotein Interaction Partners

Human Dentin Sialophosphoprotein (DSPP) interaction partners

  1. This study expands the spectrum of DSPP variants, highlighting their associated phenotypic continuum.

  2. These data indicate that secretome derived from salivary gland cancer cells can influence the expression of two potential biomarkers of oral cancer-namely, bone sialoprotein (show CRISP1 Antibodies) (BSP (show KLK6 Antibodies)) and dentin sialoprotein (DSP)-in normal salivary gland cells.

  3. DSPP-MMP20 (show MMP20 Antibodies) pair may play a role in the normal turnover of cell surface proteins and/or repair of pericellular matrix proteins of the basement membranes in the metabolically active duct epithelial system of the nephrons.

  4. BMP2 (show BMP2 Antibodies) and RUNX2 (show RUNX2 Antibodies) are expressed exclusively by osteoblasts whereas DSPP and LOXL2 (show LOXL2 Antibodies) are expressed exclusively by odontoblasts. (Review)

  5. A novel pathogenic splicing-mutation c.52-1G>A of DSPP is associated with dentinogenesis imperfecta shields type II.

  6. expression of MMP-20 and co-expression and potential interaction with DSPP in human major salivary gland tissues

  7. mutations of the DSP-PP P4 to P4' cleavage site can block, impair or accelerate dentin sialoprotein phosphophoryn cleavage, and suggest that its Bone morphogenic protein 1 cleavage site is conserved in order to regulate its cleavage efficiency

  8. DMP1 (show DMP1 Antibodies) and DSPP were more abundant in carious than in sound samples.

  9. Domain of dentine sialoprotein mediates proliferation and differentiation of human periodontal ligament stem cells.

  10. analysis of a mutation in DSPP causing dentinogenesis imperfecta and characterization of the mutational effect

Pig (Porcine) Dentin Sialophosphoprotein (DSPP) interaction partners

  1. The porcine dentin sialophosphoprotein has an N-terminal domain with at least six N-glycosylations and a C-terminal domain with two glycosaminoglycan attachments and at least two O-glycosylations.

  2. Astacins in the predentin matrix cleave Dspp.

  3. isolation of DSP from pig dentin and demonstration that it is a proteoglycan (show Vcan Antibodies)

  4. isolation and characterization of a third domain of DSPP, designated dentin glycoprotein (DGP)

  5. correspondence between DSPP cleavage sites that occur in vivo and those generated in vitro demonstrates that MMP-2 (show MMP2 Antibodies) and MMP-20 process DSPP into smaller subunits in the dentin matrix during odontogenesis

  6. DPP length variations are polymorphic and are not associated with dentin defects

  7. porcine DPP-derived arginyl-glycyl-aspartic acid peptide, but not its mutant arginyl-alanyl-aspartic acid peptide, significantly promoted cell migration

Mouse (Murine) Dentin Sialophosphoprotein (DSPP) interaction partners

  1. Results show that transgenic expression of Dspp partially rescued the long bone defects of Dmp1 (show DMP1 Antibodies)-null mice and suggest that DSPP and DMP1 (show DMP1 Antibodies) may function synergistically within the complex milieu of bone matrices.

  2. Data show provide evidence that DSPP is important for normal mineralization of both dentin and enamel.

  3. no significant dentin malformation was observed in Mep1b (show MEP1B Antibodies) (-/-) or Mep1a (show MEP1A Antibodies) (-/-) deficient mice.

  4. overexpressing DPP inhibited skeletal development, suggesting that the balanced actions between the NH2- and COOH-terminal fragments of DSPP may be required for normal skeletal development.

  5. Klf10 (show KLF10 Antibodies) is involved in tooth development and promotes odontoblastic differentiation via the up-regulation of Dmp1 (show DMP1 Antibodies) and Dspp transcription.

  6. DMOG can enhance Dspp expression through VEGF (show VEGFA Antibodies)-induced stabilization of Runx2 (show RUNX2 Antibodies) protein.

  7. total dentin volume in DSPP KO animals significant changes in the ultrastructural organization exist

  8. the expression of DSPP precursor protein is required for normal odontoblast lineage differentiation

  9. DPP is essential for the formation of well-defined tooth structures with mineralized dentin matrix.

  10. continuous DSPP action is required for the growth and/or maintenance of the mandibular condylar cartilage

Guinea Pig Dentin Sialophosphoprotein (DSPP) interaction partners

  1. The results showed that the concentrations of F ion in F and F+Al groups were increased significantly. F induced the mottled (show ATP7A Antibodies) enamel and irregular abrasion of teeth, which might occur as a consequence of depressed DSPP mRNA and DPP protein expression.

Dentin Sialophosphoprotein (DSPP) Antigen Profile

Protein Summary

This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1\; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene.

Gene names and symbols associated with DSPP

  • dentin sialophosphoprotein (DSPP) antibody
  • dentin sialophosphoprotein (Dspp) antibody
  • putative mediator of RNA polymerase II transcription subunit 26 (LOC551799) antibody
  • dentin sialophosphoprotein (Patl_2314) antibody
  • DFNA39 antibody
  • DGI1 antibody
  • Dmp2 antibody
  • Dmp3 antibody
  • Dpp antibody
  • Dsp antibody
  • DTDP2 antibody
  • RDSP2 antibody

Protein level used designations for DSPP

dentin phosphophoryn , dentin phosphoprotein , dentin phosphoryn , dentin sialoprotein , Dentin sialoprotein , Dentine sialoprotein , dentin sailophosphoprotein , dentin sialophosphoprotein , DMP-3 , dentin matrix protein 3 , LOW QUALITY PROTEIN: dentin sialophosphoprotein

1834 Homo sapiens
25254 Rattus norvegicus
396664 Sus scrofa
551799 Apis mellifera
776475 Gallus gallus
100080849 Ornithorhynchus anatinus
666279 Mus musculus
4172468 Pseudoalteromonas atlantica T6c
100337125 Bos taurus
101789124 Cavia porcellus
100683557 Canis lupus familiaris
100347075 Oryctolagus cuniculus
102189295 Capra hircus
101123300 Ovis aries musimon
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